| LDR | | 02278nmm uu200517 4500 |
| 001 | | 000000334377 |
| 005 | | 20240805180200 |
| 008 | | 181129s2016 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438309722 |
| 035 | |
▼a (MiAaPQ)AAI10970731 |
| 035 | |
▼a (MiAaPQ)OhioLINK:osu1468967532 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 082 | 0 |
▼a 610 |
| 100 | 1 |
▼a Goldstein, Evan Zachary. |
| 245 | 10 |
▼a Tlr4-Activated Microglia Have Divergent Effects on Oligodendrocyte Lineage Cells. |
| 260 | |
▼a [S.l.] :
▼b The Ohio State University.,
▼c 2016 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2016 |
| 300 | |
▼a 217 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B. |
| 500 | |
▼a Adviser: Dana McTigue. |
| 502 | 1 |
▼a Thesis (Ph.D.)--The Ohio State University, 2016. |
| 520 | |
▼a Myelin accelerates action potential conduction velocity and provides essential metabolic support for axons. Unfortunately, myelin and myelinating cells are often vulnerable to injury or disease, resulting in myelin damage, which in turn can lead |
| 520 | |
▼a Many factors produced by TLR4-activated microglia have no known effects on OL lineage cells. In chapter 3, colony stimulating factor 3 (CSF3) and interleukin 7 (IL-7) were identified as factors produced by TLR4-activated microglia that might con |
| 520 | |
▼a In chapter 4, an innate TLR4-induced iron chelation response was harnessed to sequester iron in a model of intraspinal iron accumulation. Because excess iron induces progressive neuronal and OL death, we hypothesized that intraspinal TLR4 activa |
| 590 | |
▼a School code: 0168. |
| 650 | 4 |
▼a Medicine. |
| 650 | 4 |
▼a Molecular biology. |
| 650 | 4 |
▼a Biomedical engineering. |
| 650 | 4 |
▼a Immunology. |
| 650 | 4 |
▼a Neurosciences. |
| 650 | 4 |
▼a Biology. |
| 690 | |
▼a 0564 |
| 690 | |
▼a 0307 |
| 690 | |
▼a 0541 |
| 690 | |
▼a 0982 |
| 690 | |
▼a 0317 |
| 690 | |
▼a 0306 |
| 710 | 20 |
▼a The Ohio State University.
▼b Neuroscience. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 80-01B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0168 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2016 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15001338
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자 |