MARC보기
LDR02091nmm uu200409 4500
001000000334341
00520240805180117
008181129s2018 |||||||||||||||||c||eng d
020 ▼a 9780438284272
035 ▼a (MiAaPQ)AAI10969930
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 610
1001 ▼a Smith, Samantha Kristina.
24510 ▼a Advancing Microbiosensor Development for the Real-Time Electrochemical Detection of Multiple Analytes in Rat Brain Tissue.
260 ▼a [S.l.] : ▼b North Carolina State University., ▼c 2018
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2018
300 ▼a 169 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
500 ▼a Adviser: Leslie Sombers.
5021 ▼a Thesis (Ph.D.)--North Carolina State University, 2018.
520 ▼a Actions of opiates, alcohol, and major stimulants, such as cocaine, converge on the dopaminergic systems in the brain to modify synaptic activity and behavior. The neurotransmitter dopamine is critically involved in cognition, sensorimotor integ
520 ▼a The work presented herein describes the development, characterization and utilization of microbiosensors for simultaneous detection of glucose and lactate in rat brain tissue. Investigations of enzyme attachment strategies for optimal subsecond
520 ▼a Collectively, this dissertation describes the development, characterization, and application of important new tools to advance our fundamental understanding of brain energy availability, and to elucidate how key energetic substrates respond to n
590 ▼a School code: 0155.
650 4 ▼a Biomedical engineering.
650 4 ▼a Biochemistry.
690 ▼a 0541
690 ▼a 0487
71020 ▼a North Carolina State University. ▼b Chemistry.
7730 ▼t Dissertation Abstracts International ▼g 79-12B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0155
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15001300 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자