| LDR | | 02556nmm uu200433 4500 |
| 001 | | 000000334332 |
| 005 | | 20240805180107 |
| 008 | | 181129s2018 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438283954 |
| 035 | |
▼a (MiAaPQ)AAI10969879 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 082 | 0 |
▼a 641 |
| 100 | 1 |
▼a Plundrich, Nathalie Jennifer. |
| 245 | 10 |
▼a Protein-Polyphenol Complexation to Reduce Food Protein Allergenicity. |
| 260 | |
▼a [S.l.] :
▼b North Carolina State University.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 228 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B. |
| 500 | |
▼a Advisers: Mary Ann Lila |
| 502 | 1 |
▼a Thesis (Ph.D.)--North Carolina State University, 2018. |
| 520 | |
▼a Food allergy is a worldwide health concern. Peanuts are among the "big eight" foods that can cause food allergy, and has been cited as one of the most serious and prevalent. Peanut allergy is an immunoglobulin (Ig) E-mediated hypersensitivity di |
| 520 | |
▼a Plant polyphenols are known for their natural ability to bind proteins. In previous studies, we have described a new approach to bind fruit juice- and herbal extract-derived polyphenols to peanut proteins (in the form of peanut flour), and demon |
| 520 | |
▼a In the first study, we created peanut protein-polyphenol aggregate particles containing different concentrations of polyphenols derived from cranberry (Vaccinium macrocarpon Ait.) and lowbush blueberry ( Vaccinium angustifolium Ait.) pomaces. Im |
| 520 | |
▼a One of the main peanut allergens bound by blueberry and cranberry polyphenols was Ara h 2. While our previous investigations have shown the potential of using polyphenol binding as a way to mediate allergenicity, the activities of individual pol |
| 520 | |
▼a Collectively, these findings suggest that different classes of polyphenols can both non-covalently and covalently bind to peanut allergens and consequently inhibit epitope binding by epitope-specific IgE, presenting a potential strategy for alle |
| 590 | |
▼a School code: 0155. |
| 650 | 4 |
▼a Food science. |
| 650 | 4 |
▼a Immunology. |
| 690 | |
▼a 0359 |
| 690 | |
▼a 0982 |
| 710 | 20 |
▼a North Carolina State University.
▼b Food Science. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-12B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0155 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15001291
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자 |