| LDR | | 02228nmm uu200409 4500 |
| 001 | | 000000334132 |
| 005 | | 20240805175209 |
| 008 | | 181129s2018 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438176782 |
| 035 | |
▼a (MiAaPQ)AAI10828320 |
| 035 | |
▼a (MiAaPQ)washington:18796 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 082 | 0 |
▼a 615 |
| 100 | 1 |
▼a Li, Meng. |
| 245 | 14 |
▼a The Real Option Value of Life And Innovation. |
| 260 | |
▼a [S.l.] :
▼b University of Washington.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 99 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B. |
| 500 | |
▼a Adviser: Louis Garrison. |
| 502 | 1 |
▼a Thesis (Ph.D.)--University of Washington, 2018. |
| 520 | |
▼a Background: Recent developments in healthcare value assessments have expanded the definition of value for medical technologies. The option value of a life-extending treatment is the opportunity of benefiting from future innovations during the ex |
| 520 | |
▼a Methods: In the first study, an interrupted time series analysis was conducted using a large administrative claims database to test whether the utilization of existing treatments changed after the disclosures of the then-investigational drug ipi |
| 520 | |
▼a Results: In the first study, 1,846 metastatic melanoma patients were included. After adjusting for clinical and sociodemographic variables, as well as the underlying time trend, the disclosure of ipilimumab's phase II result was associated with |
| 520 | |
▼a Conclusion: This dissertation research provided the first empirical evidence of the impact of real option value in cancer treatment decision-making. It was also the first to incorporate option value in an ex ante CEA and estimated its potential |
| 590 | |
▼a School code: 0250. |
| 650 | 4 |
▼a Pharmaceutical sciences. |
| 690 | |
▼a 0572 |
| 710 | 20 |
▼a University of Washington.
▼b Pharmacy. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-12B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0250 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14999150
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자 |