| LDR | | 00000nmm u2200205 4500 |
| 001 | | 000000334117 |
| 005 | | 20250131150401 |
| 008 | | 181129s2018 ||| | | | eng d |
| 020 | |
▼a 9780438250376 |
| 035 | |
▼a (MiAaPQ)AAI10828258 |
| 035 | |
▼a (MiAaPQ)ucsf:11639 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 049 | 1 |
▼f DP |
| 082 | 0 |
▼a 616 |
| 100 | 1 |
▼a Leib, David E. |
| 245 | 10 |
▼a Neural Control of Hunger and Thirst. |
| 260 | |
▼a [S.l.] :
▼b University of California, San Francisco.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 108 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B. |
| 500 | |
▼a Advisers: Zachary A. Knight |
| 502 | 1 |
▼a Thesis (Ph.D.)--University of California, San Francisco, 2018. |
| 520 | |
▼a Animals must maintain internal state within narrow limits to survive. This process, known as homeostasis, is coordinated by specialized neural circuits that sense deviations in internal state and respond with compensatory physiological and behav |
| 520 | |
▼a In our first study, we identify forebrain neural populations that are activated by dehydration, including an excitatory population in the median preoptic nucleus (MnPO). We show that activation of these neurons promotes drinking and increases bl |
| 520 | |
▼a In our second study, we examine dietary amino acid sensing in mice. Prior to our work, it was proposed that animals rejected food lacking a single essential amino acid (EAA) within minutes of feeding. However, we are unable to replicate this res |
| 520 | |
▼a Together, the work described in this dissertation sheds light on neural control of feeding and drinking behavior. It will be important in future studies to elucidate the neural circuit downstream of the MnPO that controls thirst and the mechanis |
| 590 | |
▼a School code: 0034. |
| 650 | 4 |
▼a Neurosciences. |
| 690 | |
▼a 0317 |
| 710 | 20 |
▼a University of California, San Francisco.
▼b Neuroscience. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-12B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0034 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14999137
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자
▼b 정현우 |