LDR | | 02099nmm uu200421 4500 |
001 | | 000000334113 |
005 | | 20240805175147 |
008 | | 181129s2018 |||||||||||||||||c||eng d |
020 | |
▼a 9780438250369 |
035 | |
▼a (MiAaPQ)AAI10828209 |
035 | |
▼a (MiAaPQ)ucsf:11638 |
040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
082 | 0 |
▼a 614.4 |
100 | 1 |
▼a Ray, Kathryn. |
245 | 10 |
▼a Innovative Microbial Outcomes in Randomized Control Trials. |
260 | |
▼a [S.l.] :
▼b University of California, San Francisco.,
▼c 2018 |
260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
300 | |
▼a 76 p. |
500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B. |
500 | |
▼a Adviser: Thomas M. Lietman. |
502 | 1 |
▼a Thesis (Ph.D.)--University of California, San Francisco, 2018. |
520 | |
▼a Randomized Control Trials (RCTs) in infectious disease can use a clinical outcome or a microbiological surrogate outcome. While caregivers are more interested in the clinical outcome, the microbiological outcome may be far more sensitive. Here I |
520 | |
▼a In chapter one, I design and analyze an experiment to compare community microbiome diversity estimates derived from 16s rRNA sequencing of 1) individually sequenced specimens versus 2) pooled specimens collected from a community. I then compare |
520 | |
▼a The estimates of community level microbiome diversity from pooled samples correlated well with estimates from individual samples. Additionally, all pooled samples fell within the 95% limits of agreement. Pooling microbiome samples to estimate co |
590 | |
▼a School code: 0034. |
650 | 4 |
▼a Epidemiology. |
650 | 4 |
▼a Public health. |
690 | |
▼a 0766 |
690 | |
▼a 0573 |
710 | 20 |
▼a University of California, San Francisco.
▼b Epidemiology and Translational Science. |
773 | 0 |
▼t Dissertation Abstracts International
▼g 79-12B(E). |
773 | |
▼t Dissertation Abstract International |
790 | |
▼a 0034 |
791 | |
▼a Ph.D. |
792 | |
▼a 2018 |
793 | |
▼a English |
856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14999131
▼n KERIS |
980 | |
▼a 201812
▼f 2019 |
990 | |
▼a 관리자 |