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020 ▼a 9780438169081
035 ▼a (MiAaPQ)AAI10825073
035 ▼a (MiAaPQ)ucsd:17510
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 616
1001 ▼a Knowland, Daniel Adam.
24510 ▼a Towards a Circuit-Based Understanding of Neuropsychiatric Disorders: Circuit-Specific Contributions to Major Depressive Disorder and Addiction.
260 ▼a [S.l.] : ▼b University of California, San Diego., ▼c 2018
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2018
300 ▼a 172 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
500 ▼a Adviser: Byungkook Lim.
5021 ▼a Thesis (Ph.D.)--University of California, San Diego, 2018.
520 ▼a Motivation directs and guides an organisms interaction with their environment and is profoundly influenced by internal brain states in conjunction with external environmental stimuli. Motivated behaviors can range from survival-based actions suc
520 ▼a However, states of pathological motivation result when proper motivational control is lost. Instances of hyper-motivation misdirected towards harmful or negative stimuli can manifest as addiction, and conversely loss of motivation and extreme ap
520 ▼a Components of the reward circuitry in the brain such as the nucleus accumbens (NAc) has been heavily studied in the context of addiction and MDD. As a central node in the reward circuitry, the NAc receives dopaminergic input from the ventral teg
590 ▼a School code: 0033.
650 4 ▼a Neurosciences.
690 ▼a 0317
71020 ▼a University of California, San Diego. ▼b Neurosciences.
7730 ▼t Dissertation Abstracts International ▼g 79-12B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0033
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T14998729 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자