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020 ▼a 9780438343863
035 ▼a (MiAaPQ)AAI10846135
035 ▼a (MiAaPQ)cornellgrad:11014
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 610
1001 ▼a DiDomenico, Christopher Dennis. ▼0 (orcid)0000-0002-3165-1354
24510 ▼a Evaluating Macromolecular Transport in Articular Cartilage to Better Understand and Predict Transport of Arthritis Therapeutics.
260 ▼a [S.l.] : ▼b Cornell University., ▼c 2018
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2018
300 ▼a 276 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
500 ▼a Adviser: Lawrence J. Bonassar.
5021 ▼a Thesis (Ph.D.)--Cornell University, 2018.
520 ▼a In the United States, joint diseases affect more than 50 million people, a number that is expected to rise in the next few decades. Hallmarks of joint disease often involve degradation of articular cartilage tissue, which leads to patient disabi
520 ▼a For proper development of effective therapeutic strategies, a better understanding of transport of larger therapeutics is needed. First, a review of molecular transport in cartilage is presented to better motivate this work (Chapter 1). There ar
590 ▼a School code: 0058.
650 4 ▼a Biomedical engineering.
650 4 ▼a Bioengineering.
650 4 ▼a Biomechanics.
690 ▼a 0541
690 ▼a 0202
690 ▼a 0648
71020 ▼a Cornell University. ▼b Biomedical Engineering.
7730 ▼t Dissertation Abstracts International ▼g 80-01B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0058
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15000114 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자