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020 ▼a 9780438125452
035 ▼a (MiAaPQ)AAI10902938
035 ▼a (MiAaPQ)umichrackham:001208
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 574
1001 ▼a Dharmarajan, Sai Hurrish.
24510 ▼a Methods for Clustered Competing Risks Data and Causal Inference using Instrumental Variables for Censored Time-to-event Data.
260 ▼a [S.l.] : ▼b University of Michigan., ▼c 2018
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2018
300 ▼a 127 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
500 ▼a Adviser: Douglas E. Schaubel.
5021 ▼a Thesis (Ph.D.)--University of Michigan, 2018.
520 ▼a In this dissertation, we propose new methods for analysis of clustered competing risks data (Chapters 1 and 2) and for instrumental variable (IV) analysis of univariate censored time-to-event data and competing risks data (Chapters 3 and 4).
520 ▼a In Chapter 1, we propose estimating center effects through cause-specific proportional hazards frailty models that allow correlation among a center's cause-specific effects. To evaluate center performance, we propose a directly standardized exce
520 ▼a In Chapter 2, we propose to model the effects of cluster and individual-level covariates directly on the cumulative incidence functions of each risk through a semiparametric mixture component model with cluster-specific random effects. Our model
520 ▼a In Chapter 3, we turn our focus to causal inference in the censored time-to-event setting in the presence of unmeasured confounders. We develop weighted IV estimators of the complier average causal effect on the restricted mean survival time. Ou
520 ▼a In Chapter 4, we develop IV analysis methods for competing risks data. Our method permits simultaneous inference of exposure effects on the absolute risk of all competing events and accommodates exposure dependent censoring. We apply the methods
590 ▼a School code: 0127.
650 4 ▼a Biostatistics.
690 ▼a 0308
71020 ▼a University of Michigan. ▼b Biostatistics.
7730 ▼t Dissertation Abstracts International ▼g 79-12B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0127
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15000448 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자