| LDR | | 01832nmm uu200409 4500 |
| 001 | | 000000333808 |
| 005 | | 20240805174558 |
| 008 | | 181129s2018 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438126855 |
| 035 | |
▼a (MiAaPQ)AAI10903079 |
| 035 | |
▼a (MiAaPQ)umichrackham:001163 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 082 | 0 |
▼a 547 |
| 100 | 1 |
▼a Gilbert, Michael M. |
| 245 | 10 |
▼a Development of Biocatalytic Strategies for the Directed Oxidation of Small Molecule and Macrocyclic Substrates. |
| 260 | |
▼a [S.l.] :
▼b University of Michigan.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 233 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B. |
| 500 | |
▼a Adviser: John Montgomery. |
| 502 | 1 |
▼a Thesis (Ph.D.)--University of Michigan, 2018. |
| 520 | |
▼a The cytochrome P450 enzyme PikC has been explored as a robust biocatalyst for late-stage directed C-H hydroxylation reactions in organic synthesis. A collaborative effort between the Sherman, Houk, Podust, and Montgomery labs has resulted in the |
| 520 | |
▼a Previous studies had illustrated that unnatural substrates can be designed to enable the oxidation of inert C-H bonds. However, the ability to tune and reverse the regioselectivity of oxidations was not possible in prior efforts. This dissertati |
| 590 | |
▼a School code: 0127. |
| 650 | 4 |
▼a Organic chemistry. |
| 650 | 4 |
▼a Molecular chemistry. |
| 690 | |
▼a 0490 |
| 690 | |
▼a 0431 |
| 710 | 20 |
▼a University of Michigan.
▼b Chemistry. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-12B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0127 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15000575
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자 |