| LDR | | 00000nmm u2200205 4500 |
| 001 | | 000000333590 |
| 005 | | 20250117142126 |
| 008 | | 181129s2018 ||| | | | eng d |
| 020 | |
▼a 9780438294868 |
| 035 | |
▼a (MiAaPQ)AAI10750289 |
| 035 | |
▼a (MiAaPQ)uci:14992 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 049 | 1 |
▼f DP |
| 082 | 0 |
▼a 610 |
| 100 | 1 |
▼a Wang, Mingqiu. |
| 245 | 10 |
▼a Kinetic Studies of Multivalent Nanoparticle Adhesion. |
| 260 | |
▼a [S.l.] :
▼b University of California, Irvine.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 147 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B. |
| 500 | |
▼a Adviser: Jered Haun. |
| 502 | 1 |
▼a Thesis (Ph.D.)--University of California, Irvine, 2018. |
| 520 | |
▼a Targeted delivery of functional nanoparticles (NPs) holds tremendous potential in diagnostics and therapeutics of vascular diseases and cancer. One of the major attributes is their ability of forming multiple bonds with target cells, thereby pro |
| 520 | |
▼a In this work, we first developed Nano adhesive dynamics (NAD) simulation to investigate the binding dynamics between an antibody-conjugated, 210-nm-diameter sphere and an ICAM-1-coated surface. In the NAD simulation, the particle motions are det |
| 520 | |
▼a In order to understand the influence of NP bonding heterogeneity on adhesion dynamics, we further examined NP detachment behaviors at higher resolutions: at sub-population level, in which we grouped NPs with similar bonding ability as in one bon |
| 590 | |
▼a School code: 0030. |
| 650 | 4 |
▼a Biomedical engineering. |
| 690 | |
▼a 0541 |
| 710 | 20 |
▼a University of California, Irvine.
▼b Biomedical Engineering - Ph.D.. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 80-01B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0030 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14997094
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자
▼b 관리자 |