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020 ▼a 9780438325050
035 ▼a (MiAaPQ)AAI10817530
035 ▼a (MiAaPQ)berkeley:17922
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 574
1001 ▼a Chiba, Kunitoshi.
24510 ▼a Decoding the Mechanisms of Cancer and Stem Cell Immortality.
260 ▼a [S.l.] : ▼b University of California, Berkeley., ▼c 2018
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2018
300 ▼a 130 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
500 ▼a Adviser: Dirk Hockemeyer.
5021 ▼a Thesis (Ph.D.)--University of California, Berkeley, 2018.
520 ▼a Telomeres are the repetitive sequences at the ends of linear chromosomes. The key functions of telomeres are to protect the cells from losing genomic information and to prevent chromosome ends from being repaired by the double strand break repai
520 ▼a Recently, point mutations in the TERT promoter were identified as the most frequent non-coding mutations in cancer. To elucidate the role of TERT promoter mutations (TPMs) in tumorigenesis, I genetically engineered these TPMs into human embryoni
590 ▼a School code: 0028.
650 4 ▼a Biology.
650 4 ▼a Cellular biology.
650 4 ▼a Oncology.
690 ▼a 0306
690 ▼a 0379
690 ▼a 0992
71020 ▼a University of California, Berkeley. ▼b Molecular & Cell Biology.
7730 ▼t Dissertation Abstracts International ▼g 80-01B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0028
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T14998375 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자