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020 ▼a 9780438116955
035 ▼a (MiAaPQ)AAI10817127
035 ▼a (MiAaPQ)northwestern:14153
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 574
1001 ▼a Prasasya, Rexxi Diptya.
24510 ▼a Regulation of Ovarian Granulosa Cell Proliferation and Differentiation by the Notch Signaling Pathway.
260 ▼a [S.l.] : ▼b Northwestern University., ▼c 2018
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2018
300 ▼a 329 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
500 ▼a Adviser: Kelly E. Mayo.
5021 ▼a Thesis (Ph.D.)--Northwestern University, 2018.
520 ▼a The follicle is the functional unit of the mammalian ovary and serves as a tightly controlled microenvironment where granulosa cells nurture the growth and maturation of the oocyte. Early events in follicular development are autonomous of the hy
520 ▼a The Notch pathway is a highly conserved cell-contact dependent juxtacrine signaling system and is an important regulator of primordial follicle formation in the mouse ovary. Using a reporter mouse line for identification of Notch active cells, c
520 ▼a Notch activity and expression of Notch ligands and receptors in the ovary were shown to be positively regulated following LH-receptor activation by exogenous human chorionic gonadotropin (hCG) in prepubertal mice during the periovulatory period.
590 ▼a School code: 0163.
650 4 ▼a Molecular biology.
650 4 ▼a Cellular biology.
690 ▼a 0307
690 ▼a 0379
71020 ▼a Northwestern University. ▼b Biological Sciences.
7730 ▼t Dissertation Abstracts International ▼g 79-11B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0163
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T14998329 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자