LDR | | 02105nmm uu200397 4500 |
001 | | 000000333398 |
005 | | 20240805172943 |
008 | | 181129s2018 |||||||||||||||||c||eng d |
020 | |
▼a 9780438125148 |
035 | |
▼a (MiAaPQ)AAI10816936 |
035 | |
▼a (MiAaPQ)northwestern:14145 |
040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
082 | 0 |
▼a 621 |
100 | 1 |
▼a Ma, Dan.
▼0 (orcid)0000-0001-9701-2750 |
245 | 10 |
▼a Investigation of Polymer Conjugated Helix Bundle Peptides to Design Micellar Nanocarriers with Tunable Size and Stability using Molecular Dynamics. |
260 | |
▼a [S.l.] :
▼b Northwestern University.,
▼c 2018 |
260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
300 | |
▼a 131 p. |
500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B. |
500 | |
▼a Adviser: Sinan Keten. |
502 | 1 |
▼a Thesis (Ph.D.)--Northwestern University, 2018. |
520 | |
▼a Hybrid polymer-peptide conjugates are receiving increasing attention as a promising class of biomaterials. Polymer conjugated coiled-coil peptides are a new addition to these designer macromolecules. Even though a variety of experiments and comp |
520 | |
▼a Building on these findings, we focus on a recent design that has utilized end-conjugation of alkyl chains to 3-helix coiled-coils to achieve amphiphilicity, combined with the side-chain conjugation of polyethylene glycol (PEG) to tune micelle si |
520 | |
▼a Homomeric micelles with tunable size, shape and stability have been extensively studied for biomedical applications such as drug carriers. However, designing the local valency and self-assembled morphology of nanophase-separated multicomponent m |
590 | |
▼a School code: 0163. |
650 | 4 |
▼a Mechanical engineering. |
690 | |
▼a 0548 |
710 | 20 |
▼a Northwestern University.
▼b Mechanical Engineering. |
773 | 0 |
▼t Dissertation Abstracts International
▼g 79-11B(E). |
773 | |
▼t Dissertation Abstract International |
790 | |
▼a 0163 |
791 | |
▼a Ph.D. |
792 | |
▼a 2018 |
793 | |
▼a English |
856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14998302
▼n KERIS |
980 | |
▼a 201812
▼f 2019 |
990 | |
▼a 관리자 |