| LDR | | 02408nmm uu200457 4500 |
| 001 | | 000000333246 |
| 005 | | 20240805172653 |
| 008 | | 181129s2018 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438116528 |
| 035 | |
▼a (MiAaPQ)AAI10815237 |
| 035 | |
▼a (MiAaPQ)northwestern:14116 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 082 | 0 |
▼a 530 |
| 100 | 1 |
▼a Zhang, Di. |
| 245 | 10 |
▼a Development of Spectroscopic Microscopy to Quantify Nanoarchitectural Changes in Biological Cells. |
| 260 | |
▼a [S.l.] :
▼b Northwestern University.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 119 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B. |
| 500 | |
▼a Adviser: Vadim Backman. |
| 502 | 1 |
▼a Thesis (Ph.D.)--Northwestern University, 2018. |
| 520 | |
▼a Cancer is the second leading cause of human deaths in the United States. Detection of early-stage cancer has been widely recognized as one of the most critical factors to successfully treat cancer and reduce mortality. Current gold standards for |
| 520 | |
▼a Facilitated by three-dimensional, full-vector finite-difference time-domain (FDTD) computational solutions of Maxwell's equations, our group has developed a novel optical microscopy technique, Partial Wave Spectroscopic (PWS) microscopy, that ca |
| 520 | |
▼a Despite the success of PWS, it made simple assumptions about the model of cells and instrument. For example, it assumes the cell has flat surfaces and the microscope has an illumination NA of 0. Additionally, the effect of biological staining on |
| 520 | |
▼a In this dissertation, we expand the theory to include more realistic models of cells and instrument and validate rigorously via FDTD simulations. The results from these theoretical developments will provide essential information to optimize PWS |
| 590 | |
▼a School code: 0163. |
| 650 | 4 |
▼a Computational physics. |
| 650 | 4 |
▼a Biomedical engineering. |
| 650 | 4 |
▼a Medical imaging. |
| 690 | |
▼a 0216 |
| 690 | |
▼a 0541 |
| 690 | |
▼a 0574 |
| 710 | 20 |
▼a Northwestern University.
▼b Biomedical Engineering. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-11B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0163 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14998162
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자 |