| LDR | | 02579nmm uu200445 4500 |
| 001 | | 000000333058 |
| 005 | | 20240805172117 |
| 008 | | 181129s2018 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438158450 |
| 035 | |
▼a (MiAaPQ)AAI10791876 |
| 035 | |
▼a (MiAaPQ)umd:18990 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 082 | 0 |
▼a 540 |
| 100 | 1 |
▼a Plank, Taylor N. |
| 245 | 10 |
▼a Tailoring Guanosine Hydrogels for Various Functions. |
| 260 | |
▼a [S.l.] :
▼b University of Maryland, College Park.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 146 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B. |
| 500 | |
▼a Adviser: Jeffery T. Davis. |
| 502 | 1 |
▼a Thesis (Ph.D.)--University of Maryland, College Park, 2018. |
| 520 | |
▼a Supramolecular hydrogels are of current interest for their ease of use, potential biocompatibility, and reactivity to stimuli. These gel materials have found use in a number of fields ranging from drug delivery and tissue engineering to sensing |
| 520 | |
▼a Modification of the 5'-OH group of G 1 to form 5'-deoxy-5'-iodoguanosine (5'-IG 2) results in a hydrogel that self-destructs via intramolecular cyclization to 5'-deoxy-N3,5'-cycloguanosine (5'-cG 3). Guanine analog drugs can be incorporated int |
| 520 | |
▼a Substitution of boric acid with benzene-1,4-diboronic acid (BDBA 4) to form hydrogels with G 1 and K+ results in hydrogels that can be crosslinked with Mg2+. These G-BDBA-Mg hydrogels have a lower critical gelator concentration (cgc) than their |
| 520 | |
▼a Utilizing binary mixtures of 8-aminoguanosine (8AmG 5) with G 1 allows for the formation of hydrogels with various salts. Hydrogels made of different salts preferentially absorb either cationic or anionic dyes from water, making them candidates |
| 520 | |
▼a Other 8-substituted G-analogs, including, 8-bromoguanosine (8BrG 6), 8-iodoguanosine (8IG 7), and 8-morpholinoguanosine (8morphG 8) can be used in binary mixtures with G 1 to form gels at room temperature upon mixing with KB(OH)4. Room temperat |
| 590 | |
▼a School code: 0117. |
| 650 | 4 |
▼a Chemistry. |
| 650 | 4 |
▼a Organic chemistry. |
| 690 | |
▼a 0485 |
| 690 | |
▼a 0490 |
| 710 | 20 |
▼a University of Maryland, College Park.
▼b Chemistry. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-11B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0117 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14997668
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자 |