MARC보기
LDR02093nmm uu200445 4500
001000000332820
00520240805171640
008181129s2018 |||||||||||||||||c||eng d
020 ▼a 9780438067523
035 ▼a (MiAaPQ)AAI10809639
035 ▼a (MiAaPQ)bu:13856
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 616.079
1001 ▼a Pavlovich, Stephanie Sarah.
24510 ▼a Genomic Analysis and Examination of Innate Antiviral Immunity in the Egyptian Rousette Bat.
260 ▼a [S.l.] : ▼b Boston University., ▼c 2018
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2018
300 ▼a 201 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
500 ▼a Adviser: Thomas B. Kepler.
5021 ▼a Thesis (Ph.D.)--Boston University, 2018.
520 ▼a Bats asymptomatically host a number of viruses that are the cause of recently emergent infectious diseases in humans. While the mechanisms underlying this asymptomatic infection are currently not known, studies of sequenced bat genomes help unco
520 ▼a We observed an unusual expansion of the NKG2/CD94 natural killer (NK) cell receptor gene families in Egyptian rousette bats relative to other species, and found genomic evidence of unique features and expression of these receptors that may resul
520 ▼a Taken together, these results show that multiple bats, including the ERB, have expanded and diversified numerous antiviral loci, and potentially developed unique adaptations in NK cell receptor signaling, and type I IFN responses. The concerted
590 ▼a School code: 0017.
650 4 ▼a Immunology.
650 4 ▼a Genetics.
650 4 ▼a Virology.
690 ▼a 0982
690 ▼a 0369
690 ▼a 0720
71020 ▼a Boston University. ▼b Microbiology.
7730 ▼t Dissertation Abstracts International ▼g 79-11B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0017
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T14997896 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자