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008181129s2018 ||| | | | eng d
020 ▼a 9780438239524
035 ▼a (MiAaPQ)AAI10809863
035 ▼a (MiAaPQ)coe.neu:10993
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0491 ▼f DP
0820 ▼a 660
1001 ▼a Zhang, Junyan.
24510 ▼a Biomedical Applications of Gold and Silver Nanoparticles.
260 ▼a [S.l.] : ▼b Northeastern University., ▼c 2018
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2018
300 ▼a 131 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
500 ▼a Adviser: Thomas J. Webster.
5021 ▼a Thesis (Ph.D.)--Northeastern University, 2018.
520 ▼a Noble nanoparticles have attracted a large amount of attention among researchers due to their brilliant colors, which results from their unique optical properties from the localized surface plasmon resonance (LSPR) effect. Among different kinds
520 ▼a The unique optical properties of gold nanoparticles (AuNPs) depend on many different factors, such as the size and shape of the nanoparticles. Besides unique optical properties, AuNPs can be easily modified and conjugated with different kinds of
520 ▼a Silver nanoparticles (AgNPs) have been widely investigated as a promising antimicrobial agent after recent advances in nanotechnology. However, AgNPs have been found to cause cytotoxicity to mammalian cells in a dose-dependent manner. Therefore,
520 ▼a In the current study, AuNRs were first synthesized, characterized and tested on healthy mammalian cells and tumor cells. Results showed that synthesized AuNRs were highly toxic towards tumor cells and at the same time had little or no influence
520 ▼a Next, silver-coated AuNRs (Ag/AuNRs) were synthesized in order to employ the antimicrobial properties of silver. Their antimicrobial properties were tested on different bacteria species. Furthermore, TEM images showed "pits" on the treated S. au
520 ▼a Finally, some other shapes of nanoparticles, gold nanospheres and gold nanostars, were synthesized and characterized. Results showed limited tunability of gold nanospheres in their absorption band. However, they have the potential to be used as
590 ▼a School code: 0160.
650 4 ▼a Chemical engineering.
690 ▼a 0542
71020 ▼a Northeastern University. ▼b Chemical Engineering.
7730 ▼t Dissertation Abstracts International ▼g 79-12B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0160
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T14997907 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자 ▼b 관리자