| LDR | | 02514nmm uu200421 4500 |
| 001 | | 000000332556 |
| 005 | | 20240805171019 |
| 008 | | 181129s2018 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438063556 |
| 035 | |
▼a (MiAaPQ)AAI10788637 |
| 035 | |
▼a (MiAaPQ)unc:17673 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 082 | 0 |
▼a 614.4 |
| 100 | 1 |
▼a Landi, Suzanne Noelle. |
| 245 | 10 |
▼a Comparative Effectiveness and Safety of Metformin Versus Insulin for Gestational Diabetes Treatment: Maternal, Neonatal, and Child Health Outcomes. |
| 260 | |
▼a [S.l.] :
▼b The University of North Carolina at Chapel Hill.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 125 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B. |
| 500 | |
▼a Adviser: Michele Jonsson Funk. |
| 502 | 1 |
▼a Thesis (Ph.D.)--The University of North Carolina at Chapel Hill, 2018. |
| 520 | |
▼a Background: Metformin is an emerging option for treating gestational diabetes (GDM). The evidence for the comparative safety and effectiveness of metformin versus insulin (standard of care) is inconclusive. |
| 520 | |
▼a Objective: To measure the comparative safety and effectiveness of metformin versus insulin for pharmacological management of GDM. |
| 520 | |
▼a Methods: We conducted a cohort study using New Zealand healthcare data (2005-2015). We identified pregnant women treated with metformin or insulin for GDM and excluded women with evidence of preexisting diabetes. We assessed birth outcomes using |
| 520 | |
▼a Results: We identified 7,268 pregnancies treated initially with metformin (n=3,818) or insulin (n=3,450). Treatment initiation varied by ethnicity, socioeconomic status, region and calendar year, though both groups were similar with respect to a |
| 520 | |
▼a Conclusions: Metformin appears to be an effective treatment for women with GDM and may reduce the risk of some adverse neonatal outcomes when compared to insulin. Growth assessments of children of metformin-treated mothers were similar to those |
| 590 | |
▼a School code: 0153. |
| 650 | 4 |
▼a Epidemiology. |
| 690 | |
▼a 0766 |
| 710 | 20 |
▼a The University of North Carolina at Chapel Hill.
▼b Epidemiology. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-10B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0153 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14997464
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자 |