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LDR02069nmm uu200421 4500
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008181129s2018 |||||||||||||||||c||eng d
020 ▼a 9780438066991
035 ▼a (MiAaPQ)AAI10787032
035 ▼a (MiAaPQ)bu:13723
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 616.079
1001 ▼a Kadasia, Kadryn D.
24514 ▼a The Functional Role of Naturally Occurring Antibodies Against HIV-1 in Human Genital Mucosa.
260 ▼a [S.l.] : ▼b Boston University., ▼c 2018
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2018
300 ▼a 229 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
500 ▼a Advisers: Deborah J. Anderson
5021 ▼a Thesis (Ph.D.)--Boston University, 2018.
520 ▼a Sexual transmission of the Human Immunodeficiency Virus Type 1 (HIV-1) accounts for the majority of newly acquired infections. Vaccination efforts have induced only modest protection in HIV clinical trials. HIV-1 induces a robust local immune re
520 ▼a This study focused on HIV-specific antibody responses in the male genital tract (MGT), which is underexplored. We characterized antibody subclasses and specificities in genital tract secretions (seminal plasma, urethral secretions) and blood fro
520 ▼a To explore cell-dependent activities of HIV-specific antibodies in genital mucosa we surveyed Fc receptor expression in mucosal epithelial tissue. The IgG-engaging neonatal Fc receptor (FcRn), the IgA receptor FcalphaRI and the high-affinity int
590 ▼a School code: 0017.
650 4 ▼a Immunology.
650 4 ▼a Medicine.
690 ▼a 0982
690 ▼a 0564
71020 ▼a Boston University. ▼b Molecular and Translational Medicine GMS.
7730 ▼t Dissertation Abstracts International ▼g 79-10B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0017
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T14997377 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자