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020 ▼a 9780438079281
035 ▼a (MiAaPQ)AAI10829373
035 ▼a (MiAaPQ)wisc:15405
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 616
1001 ▼a Frost, Carlton P., VI.
24510 ▼a Childhood Emotional Abuse and Neuroendocrine Stress Systems in Depression: A Possible Role for Corticomotor Circuitry.
260 ▼a [S.l.] : ▼b The University of Wisconsin - Madison., ▼c 2018
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2018
300 ▼a 121 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
500 ▼a Advisers: Heather C. Abercrombie
5021 ▼a Thesis (Ph.D.)--The University of Wisconsin - Madison, 2018.
520 ▼a The activity of neuroendocrine stress systems, and their effects on memory formation & neuroplasticity, are altered in depression. Research in animal models shows early life adversity alters corticosteroids' effects on memory formation and neuro
520 ▼a In a double-blind crossover study, functional magnetic resonance imaging (fMRI) was used to assess the neural correlates of the effects of cortisol administration (CORT), vs Placebo, on memory formation for emotional pictures. In addition, I use
520 ▼a Only in women with history of severe EA, CORT eliminated the relation between depression severity and negative memory bias by normalizing recall for pleasant stimuli. These women showed a related increase in BOLD activation in cortical premotor
520 ▼a Thus, I demonstrate evidence of distinct neurocognitive responses to acute cortisol elevation in depressed women with history of EA, who may comprise an etiologically distinct subtype of depression, and whose emotional learning is partly normali
590 ▼a School code: 0262.
650 4 ▼a Neurosciences.
650 4 ▼a Psychology.
650 4 ▼a Endocrinology.
690 ▼a 0317
690 ▼a 0621
690 ▼a 0409
71020 ▼a The University of Wisconsin - Madison. ▼b Neuroscience.
7730 ▼t Dissertation Abstracts International ▼g 79-11B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0262
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T14999296 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자