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LDR01612nmm uu200421 4500
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008181129s2018 |||||||||||||||||c||eng d
020 ▼a 9780438077485
035 ▼a (MiAaPQ)AAI10826710
035 ▼a (MiAaPQ)indiana:15258
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 616.99
1001 ▼a Pulliam, Nicholas.
24513 ▼a An Effective Epigenetic-PARP Inhibitor Combination Therapy for Breast and Ovarian Cancers Independent of BRCA-Mutations.
260 ▼a [S.l.] : ▼b Indiana University., ▼c 2018
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2018
300 ▼a 186 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
500 ▼a Adviser: Kenneth P. Nephew.
5021 ▼a Thesis (Ph.D.)--Indiana University, 2018.
520 ▼a Poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi) are primarily effective against BRCA1/2-mutated ovarian and breast cancers, but resistance due to reversion of mutated BRCA1/2 and other mechanisms is common. Based on previous reports demon
590 ▼a School code: 0093.
650 4 ▼a Oncology.
650 4 ▼a Molecular biology.
650 4 ▼a Cellular biology.
690 ▼a 0992
690 ▼a 0307
690 ▼a 0379
71020 ▼a Indiana University. ▼b Biochemistry.
7730 ▼t Dissertation Abstracts International ▼g 79-11B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0093
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T14998929 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자