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020 ▼a 9780438125551
035 ▼a (MiAaPQ)AAI10902948
035 ▼a (MiAaPQ)umichrackham:001117
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 612
1001 ▼a Emont, Margo P.
24510 ▼a Subcutaneous Fat: Thermogenesis and Metabolic Benefits.
260 ▼a [S.l.] : ▼b University of Michigan., ▼c 2017
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2017
300 ▼a 119 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
500 ▼a Adviser: Jun Wu.
5021 ▼a Thesis (Ph.D.)--University of Michigan, 2017.
520 ▼a Obesity and its associated metabolic diseases present a major public health problem around the world. The discovery that thermogenic fat is active in adult humans has sparked a renewal of interest in the study of its development and function and
520 ▼a It has long been recognized that body fat distribution and regional adiposity play a major role in the control of metabolic homeostasis. However, the ability to study and compare the cell autonomous regulation and response of adipocytes from dif
520 ▼a Cinnamaldehyde (CA) is a food compound that has previously been observed to be protective against obesity and hyperglycemia. In the second part of my thesis work, I report that CA activates a thermogenic response via PKA signaling in murine subc
520 ▼a The potential of the adipocyte in the understanding and treatment of human physiology in health and disease is clearly as of yet not fully realized. Here, I have provided a method to further study the differences between subcutaneous and viscera
590 ▼a School code: 0127.
650 4 ▼a Physiology.
690 ▼a 0719
71020 ▼a University of Michigan. ▼b Molecular and Integrative Physiology.
7730 ▼t Dissertation Abstracts International ▼g 79-12B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0127
791 ▼a Ph.D.
792 ▼a 2017
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15000457 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자