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020 ▼a 9780438125520
035 ▼a (MiAaPQ)AAI10902945
035 ▼a (MiAaPQ)umichrackham:001126
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 574
1001 ▼a Eksi, Ridvan.
24510 ▼a Identification and Functional Annotation of Alternatively Spliced Isoforms.
260 ▼a [S.l.] : ▼b University of Michigan., ▼c 2017
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2017
300 ▼a 137 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
500 ▼a Adviser: Yuanfang Guan.
5021 ▼a Thesis (Ph.D.)--University of Michigan, 2017.
520 ▼a Alternative splicing is a key mechanism for increasing the complexity of transcriptome and proteome in eukaryotic cells. A large portion of multi-exon genes in humans undergo alternative splicing, and this can have significant functional consequ
520 ▼a In the first chapter, I give an introduction of alternative splicing and discuss the existing studies where next generation sequencing is used for transcript identification. Then, I define the isoform function prediction problem, and explain how
590 ▼a School code: 0127.
650 4 ▼a Bioinformatics.
690 ▼a 0715
71020 ▼a University of Michigan. ▼b Bioinformatics.
7730 ▼t Dissertation Abstracts International ▼g 79-12B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0127
791 ▼a Ph.D.
792 ▼a 2017
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15000455 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자