| LDR | | 00000nmm u2200205 4500 |
| 001 | | 000000331766 |
| 005 | | 20241120141728 |
| 008 | | 181129s2018 ||| | | | eng d |
| 020 | |
▼a 9780438403796 |
| 035 | |
▼a (MiAaPQ)AAI10935608 |
| 035 | |
▼a (MiAaPQ)wisc:15790 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 049 | 1 |
▼f DP |
| 082 | 0 |
▼a 310 |
| 100 | 1 |
▼a Chen, Kailei. |
| 245 | 10 |
▼a Simultaneous Analysis of Large Scale Datasets in Different ChIP-seq Problem Settings. |
| 260 | |
▼a [S.l.] :
▼b The University of Wisconsin - Madison.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 85 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 80-02(E), Section: B. |
| 500 | |
▼a Adviser: Sunduz Keles. |
| 502 | 1 |
▼a Thesis (Ph.D.)--The University of Wisconsin - Madison, 2018. |
| 520 | |
▼a Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is a common genomics tool for studying regulation of transcription. Analyses of ChIP-seq data typically concern: i) binding state inference, which aims at detecting the DNA loci occ |
| 520 | |
▼a Chapter 2 introduces a MAP-based Asymptotic Derivations from Bayes (MAD-Bayes) method based on strong assumptions in MBASIC framework. This results in a K-means-like optimization algorithm which converges rapidlyThe fast-converging nature enable |
| 520 | |
▼a In Chapter 3, I extends the MAD-Bayes MBASIC to the allele-specific analysis setting, via a variance-stabilizing transformation, enabling the method to apply discrete distributions in both binding state and allele-specific binding problems. Appl |
| 590 | |
▼a School code: 0262. |
| 650 | 4 |
▼a Statistics. |
| 690 | |
▼a 0463 |
| 710 | 20 |
▼a The University of Wisconsin - Madison.
▼b Statistics. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 80-02B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0262 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15001196
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자
▼b 관리자 |