| LDR | | 02087nmm uu200421 4500 |
| 001 | | 000000331692 |
| 005 | | 20240805164913 |
| 008 | | 181129s2018 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438380233 |
| 035 | |
▼a (MiAaPQ)AAI10932818 |
| 035 | |
▼a (MiAaPQ)ucla:17193 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 082 | 0 |
▼a 616 |
| 100 | 1 |
▼a Frohlich, Joel. |
| 245 | 10 |
▼a Neurophysiological Oscillations as Biomarkers of Neurodevelopmental Disorders. |
| 260 | |
▼a [S.l.] :
▼b University of California, Los Angeles.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 210 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B. |
| 500 | |
▼a Adviser: Shafali S. Jeste. |
| 502 | 1 |
▼a Thesis (Ph.D.)--University of California, Los Angeles, 2018. |
| 520 | |
▼a Mechanism-based biomarkers are needed to guide clinical trials for neurodevelopmental disorders by indexing disease pathology or a treatment response. In this dissertation, I describe electroencephalogram (EEG) biomarkers in two neurodevelopment |
| 520 | |
▼a In Chapter 1, I introduce biomarkers and neurodevelopmental disorders. In Chapter 2, I infer the emergence of stable oscillations from neural noise in typically developing (TD) preschool age children. In Chapter 3, I describe a beta EEG phenotyp |
| 520 | |
▼a In conclusion, neurophysiological oscillations are likely markers of gene-specific disease pathology in Dup15q syndrome and Angelman syndrome. Clinical trials targeting specific gene products (e.g., GABAA receptors) may utilize these EEG measure |
| 590 | |
▼a School code: 0031. |
| 650 | 4 |
▼a Neurosciences. |
| 650 | 4 |
▼a Genetics. |
| 690 | |
▼a 0317 |
| 690 | |
▼a 0369 |
| 710 | 20 |
▼a University of California, Los Angeles.
▼b Neuroscience 004F. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 80-01B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0031 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15001114
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자 |