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020 ▼a 9780438312784
035 ▼a (MiAaPQ)AAI10931514
035 ▼a (MiAaPQ)wustl:12610
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 576
1001 ▼a Huynh, Jeremy Peter. ▼0 (orcid)0000-0002-1428-0686
24510 ▼a Identification of Bhlhe40 and Irg1 as Essential Regulators of the Inflammatory Response to Mycobacterium tuberculosis.
260 ▼a [S.l.] : ▼b Washington University in St. Louis., ▼c 2018
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2018
300 ▼a 155 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
500 ▼a Adviser: Christina L. Stallings.
5021 ▼a Thesis (Ph.D.)--Washington University in St. Louis, 2018.
520 ▼a Protective immune responses to Mycobacterium tuberculosis (Mtb) must induce bactericidal functions while minimizing damage to the lung. Such responses require precise control of pro- and anti-inflammatory factors to regulate the recruitment and
520 ▼a We utilized genetically deficient mice to assess the roles of Bhlhe40 and Irg1 expression on control of in vivo Mtb infection. We found that Bhlhe40 enables protective immune responses to Mtb by restricting expression of the anti-inflammatory cy
590 ▼a School code: 0252.
650 4 ▼a Microbiology.
650 4 ▼a Immunology.
690 ▼a 0410
690 ▼a 0982
71020 ▼a Washington University in St. Louis. ▼b Biology & Biomedical Sciences (Molecular Microbiology & Microbial Pathogenesis).
7730 ▼t Dissertation Abstracts International ▼g 80-01B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0252
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15001044 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자