| LDR | | 02197nmm uu200445 4500 |
| 001 | | 000000331541 |
| 005 | | 20240805164606 |
| 008 | | 181129s2018 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438345362 |
| 035 | |
▼a (MiAaPQ)AAI10929788 |
| 035 | |
▼a (MiAaPQ)cornellgrad:11122 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 082 | 0 |
▼a 610 |
| 100 | 1 |
▼a Mojica Santiago, Jorge Alexis.
▼0 (orcid)0000-0001-6350-1759 |
| 245 | 10 |
▼a Tissue Engineering of Cervical Intervertebral Discs: An in vitro and in vivo Pre-clinical Canine Model of Total Disc Replacement. |
| 260 | |
▼a [S.l.] :
▼b Cornell University.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 188 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B. |
| 500 | |
▼a Adviser: Lawrence Bonassar. |
| 502 | 1 |
▼a Thesis (Ph.D.)--Cornell University, 2018. |
| 520 | |
▼a Degeneration of the intervertebral disc (IVD) is directly associated with the leading causes of disability in the industrialized world, neck and back pain. Current treatments focus on pain relief and mitigating symptoms rather than addressing th |
| 520 | |
▼a Total disc replacement with biological tissue-engineered IVDs (TE-IVDs) has only been tested in small animal models to date. This dissertation sought to address the need for a larger animal model that is clinically relevant to humans by demonstr |
| 520 | |
▼a Despite the favorable outcomes in stably implanted TE-IVDs, new challenges were identified in the canine model that had not been encountered in rodents before. Segment instability caused 50% of TE-IVDs to displace out of the disc space upon impl |
| 590 | |
▼a School code: 0058. |
| 650 | 4 |
▼a Biomedical engineering. |
| 650 | 4 |
▼a Biomechanics. |
| 650 | 4 |
▼a Biology. |
| 690 | |
▼a 0541 |
| 690 | |
▼a 0648 |
| 690 | |
▼a 0306 |
| 710 | 20 |
▼a Cornell University.
▼b Biomedical Engineering. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 80-01B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0058 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15000960
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자 |