| LDR | | 02368nmm uu200457 4500 |
| 001 | | 000000331516 |
| 005 | | 20240805164535 |
| 008 | | 181129s2018 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438292338 |
| 035 | |
▼a (MiAaPQ)AAI10929363 |
| 035 | |
▼a (MiAaPQ)wustl:12605 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 082 | 0 |
▼a 616 |
| 100 | 1 |
▼a Hsu, Hsun-Chia. |
| 245 | 10 |
▼a In vivo Vascular Imaging with Photoacoustic Microscopy. |
| 260 | |
▼a [S.l.] :
▼b Washington University in St. Louis.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 86 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B. |
| 500 | |
▼a Adviser: Lihong V. Wang. |
| 502 | 1 |
▼a Thesis (Ph.D.)--Washington University in St. Louis, 2018. |
| 520 | |
▼a Photoacoustic (PA) tomography (PAT) has received extensive attention in the last decade for its capability to provide label-free structural and functional imaging in biological tissue with highly scalable spatial resolution and penetration depth |
| 520 | |
▼a In this dissertation, one challenge was to quantitatively investigate red-blood-cell dynamics in nailfold capillaries with single-cell resolution PA microscopy (PAM). We recruited healthy volunteers and measured multiple hemodynamic parameters b |
| 520 | |
▼a We next conducted a pilot study on sickle cell disease (SCD), measuring and comparing the parameters related to RBC dynamics between healthy subjects and patients with SCD. In the patient group, we found that capillaries tended to be more tortuo |
| 520 | |
▼a As the last focus of this dissertation, we tackled the limited view problem in PAM by introducing an off-axis illumination technique for complementing the original detection view. We demonstrated this technique numerically and then experimentall |
| 590 | |
▼a School code: 0252. |
| 650 | 4 |
▼a Medical imaging. |
| 650 | 4 |
▼a Optics. |
| 650 | 4 |
▼a Acoustics. |
| 690 | |
▼a 0574 |
| 690 | |
▼a 0752 |
| 690 | |
▼a 0986 |
| 710 | 20 |
▼a Washington University in St. Louis.
▼b Biomedical Engineering. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-12B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0252 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15000938
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자 |