MARC보기
LDR02368nmm uu200457 4500
001000000331516
00520240805164535
008181129s2018 |||||||||||||||||c||eng d
020 ▼a 9780438292338
035 ▼a (MiAaPQ)AAI10929363
035 ▼a (MiAaPQ)wustl:12605
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 616
1001 ▼a Hsu, Hsun-Chia.
24510 ▼a In vivo Vascular Imaging with Photoacoustic Microscopy.
260 ▼a [S.l.] : ▼b Washington University in St. Louis., ▼c 2018
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2018
300 ▼a 86 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
500 ▼a Adviser: Lihong V. Wang.
5021 ▼a Thesis (Ph.D.)--Washington University in St. Louis, 2018.
520 ▼a Photoacoustic (PA) tomography (PAT) has received extensive attention in the last decade for its capability to provide label-free structural and functional imaging in biological tissue with highly scalable spatial resolution and penetration depth
520 ▼a In this dissertation, one challenge was to quantitatively investigate red-blood-cell dynamics in nailfold capillaries with single-cell resolution PA microscopy (PAM). We recruited healthy volunteers and measured multiple hemodynamic parameters b
520 ▼a We next conducted a pilot study on sickle cell disease (SCD), measuring and comparing the parameters related to RBC dynamics between healthy subjects and patients with SCD. In the patient group, we found that capillaries tended to be more tortuo
520 ▼a As the last focus of this dissertation, we tackled the limited view problem in PAM by introducing an off-axis illumination technique for complementing the original detection view. We demonstrated this technique numerically and then experimentall
590 ▼a School code: 0252.
650 4 ▼a Medical imaging.
650 4 ▼a Optics.
650 4 ▼a Acoustics.
690 ▼a 0574
690 ▼a 0752
690 ▼a 0986
71020 ▼a Washington University in St. Louis. ▼b Biomedical Engineering.
7730 ▼t Dissertation Abstracts International ▼g 79-12B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0252
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15000938 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자