| LDR | | 01693nmm uu200385 4500 |
| 001 | | 000000331443 |
| 005 | | 20240805164407 |
| 008 | | 181129s2018 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438194847 |
| 035 | |
▼a (MiAaPQ)AAI10927914 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 082 | 0 |
▼a 616.079 |
| 100 | 1 |
▼a Sng, Xuan En Joel. |
| 245 | 10 |
▼a Establishment of human early B cell tolerance: Lessons from Sjogren's Syndrome and AIRE deficiency. |
| 260 | |
▼a [S.l.] :
▼b Yale University.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 190 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B. |
| 502 | 1 |
▼a Thesis (Ph.D.)--Yale University, 2018. |
| 520 | |
▼a Primary immunodeficiencies (PIDs) provide unique opportunities to study the impact of individual gene defects on the regulation of human B cell tolerance. Developing B cells with autoreactive B cell receptors (BCRs) are removed at two discrete e |
| 520 | |
▼a In chapter 1, I introduce general background and concepts of autoimmunity and discuss insights into human early B cell tolerance from prior studies of primary immunodeficiency diseases. In chapter 2, I discuss the application of these concepts i |
| 590 | |
▼a School code: 0265. |
| 650 | 4 |
▼a Immunology. |
| 650 | 4 |
▼a Health sciences. |
| 690 | |
▼a 0982 |
| 690 | |
▼a 0566 |
| 710 | 20 |
▼a Yale University. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-12B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0265 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15000862
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자 |