MARC보기
LDR02424nmm uu200457 4500
001000000331272
00520240805164044
008181129s2018 |||||||||||||||||c||eng d
020 ▼a 9780438348981
035 ▼a (MiAaPQ)AAI10840842
035 ▼a (MiAaPQ)unc:18015
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 616
1001 ▼a Brown, Logan Y.
24510 ▼a Contributions of Hippocampcal Area CA2 to Hippocampal Oscillatory Networks.
260 ▼a [S.l.] : ▼b The University of North Carolina at Chapel Hill., ▼c 2018
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2018
300 ▼a 112 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
500 ▼a Adviser: Serena M. Dudek.
5021 ▼a Thesis (Ph.D.)--The University of North Carolina at Chapel Hill, 2018.
520 ▼a Complex cognitive abilities, such as memory, require synchronized neural activity across large populations of cells. The hippocampus is a region of the brain required for the formation of long term episodic memories, which is our memory for auto
520 ▼a One mechanism for the coordination of neural networks is synchronization through oscillations. Neuronal oscillations reflect waves of synchronous action potentials and their presence in the hippocampus is strongly associated with episodic learni
520 ▼a In Chapter 2, I use Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) to manipulate the endogenous G protein-coupled receptor (GPCR) signaling pathways in CA2 while animals explore a novel spatial environment. These experiment
520 ▼a In Chapter 3, I further dissect the role of CA2 in coordinating hippocampal oscillations by inhibiting CA2 pyramidal cells while animals investigate novel social stimuli and record from CA2's primary output region, CA1. These experiments reveale
590 ▼a School code: 0153.
650 4 ▼a Neurosciences.
650 4 ▼a Molecular biology.
650 4 ▼a Biology.
690 ▼a 0317
690 ▼a 0307
690 ▼a 0306
71020 ▼a The University of North Carolina at Chapel Hill. ▼b Neurobiology.
7730 ▼t Dissertation Abstracts International ▼g 80-01B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0153
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T14999752 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자