LDR | | 02424nmm uu200457 4500 |
001 | | 000000331272 |
005 | | 20240805164044 |
008 | | 181129s2018 |||||||||||||||||c||eng d |
020 | |
▼a 9780438348981 |
035 | |
▼a (MiAaPQ)AAI10840842 |
035 | |
▼a (MiAaPQ)unc:18015 |
040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
082 | 0 |
▼a 616 |
100 | 1 |
▼a Brown, Logan Y. |
245 | 10 |
▼a Contributions of Hippocampcal Area CA2 to Hippocampal Oscillatory Networks. |
260 | |
▼a [S.l.] :
▼b The University of North Carolina at Chapel Hill.,
▼c 2018 |
260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
300 | |
▼a 112 p. |
500 | |
▼a Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B. |
500 | |
▼a Adviser: Serena M. Dudek. |
502 | 1 |
▼a Thesis (Ph.D.)--The University of North Carolina at Chapel Hill, 2018. |
520 | |
▼a Complex cognitive abilities, such as memory, require synchronized neural activity across large populations of cells. The hippocampus is a region of the brain required for the formation of long term episodic memories, which is our memory for auto |
520 | |
▼a One mechanism for the coordination of neural networks is synchronization through oscillations. Neuronal oscillations reflect waves of synchronous action potentials and their presence in the hippocampus is strongly associated with episodic learni |
520 | |
▼a In Chapter 2, I use Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) to manipulate the endogenous G protein-coupled receptor (GPCR) signaling pathways in CA2 while animals explore a novel spatial environment. These experiment |
520 | |
▼a In Chapter 3, I further dissect the role of CA2 in coordinating hippocampal oscillations by inhibiting CA2 pyramidal cells while animals investigate novel social stimuli and record from CA2's primary output region, CA1. These experiments reveale |
590 | |
▼a School code: 0153. |
650 | 4 |
▼a Neurosciences. |
650 | 4 |
▼a Molecular biology. |
650 | 4 |
▼a Biology. |
690 | |
▼a 0317 |
690 | |
▼a 0307 |
690 | |
▼a 0306 |
710 | 20 |
▼a The University of North Carolina at Chapel Hill.
▼b Neurobiology. |
773 | 0 |
▼t Dissertation Abstracts International
▼g 80-01B(E). |
773 | |
▼t Dissertation Abstract International |
790 | |
▼a 0153 |
791 | |
▼a Ph.D. |
792 | |
▼a 2018 |
793 | |
▼a English |
856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14999752
▼n KERIS |
980 | |
▼a 201812
▼f 2019 |
990 | |
▼a 관리자 |