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008181129s2018 ||| | | | eng d
020 ▼a 9780438180840
035 ▼a (MiAaPQ)AAI10839590
035 ▼a (MiAaPQ)columbia:14822
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0491 ▼f DP
0820 ▼a 614.4
1001 ▼a Work, Meghan E.
24510 ▼a Breast Cancer Risk Factors and Associations with Breast Cancer Tumor Characteristics in High Risk Populations.
260 ▼a [S.l.] : ▼b Columbia University., ▼c 2018
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2018
300 ▼a 178 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
500 ▼a Adviser: Mary Beth Terry.
5021 ▼a Thesis (Ph.D.)--Columbia University, 2018.
520 ▼a Background: Estrogen receptor (ER)- and progesterone receptor (PR)-negative (ER-PR-) breast cancer is associated with higher grade and poorer prognosis compared with other breast cancer subtypes. High parity, coupled with lack of breastfeeding,
520 ▼a Methods: Using population-based and clinic-based ascertained cases and controls from the Breast Cancer Family Registry, I examined reproductive risk factors, including parity, breastfeeding, and oral contraceptive (OC) use, in relation to ER and
520 ▼a Results: High parity (&ge
520 ▼a Conclusions: My findings support that there are modifiable factors for ER-PR- breast cancer, and that breastfeeding in particular may mitigate the increased risk of ER-PR-cancers seen from multiparity. The mechanism of both risk and risk mitigat
590 ▼a School code: 0054.
650 4 ▼a Epidemiology.
690 ▼a 0766
71020 ▼a Columbia University. ▼b Epidemiology.
7730 ▼t Dissertation Abstracts International ▼g 79-12B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0054
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T14999689 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자 ▼b 관리자