| LDR | | 02413nmm uu200457 4500 |
| 001 | | 000000331191 |
| 005 | | 20240805163611 |
| 008 | | 181129s2018 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438261051 |
| 035 | |
▼a (MiAaPQ)AAI10839132 |
| 035 | |
▼a (MiAaPQ)minarees:15135 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 082 | 0 |
▼a 150 |
| 100 | 1 |
▼a Vila-Castelar, Clara. |
| 245 | 10 |
▼a Detecting Cognitive, Functional and Behavioral Response to Donepezil in Alzheimer's Disease: The Role of Attention Tasks. |
| 260 | |
▼a [S.l.] :
▼b City University of New York.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 88 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B. |
| 500 | |
▼a Adviser: Nancy S. Foldi. |
| 502 | 1 |
▼a Thesis (Ph.D.)--City University of New York, 2018. |
| 520 | |
▼a Introduction: Cholinesterase Inhibitors (ChEIs) used in Alzheimer's Disease (AD) have modest effects, heterogeneous treatment response, and it has been difficult to detect treatment response. The standard research and clinical outcome measure, t |
| 520 | |
▼a Method: We conducted a longitudinal, open label donepezil trial assessing twenty-three participants with AD at baseline (T1), 6 weeks (T2) and 6 months (T3). Outcome measures were: a) Computerized measures of attention: Foreperiod Effect, Covert |
| 520 | |
▼a Results: Our findings show that attention measures at 6 weeks (T2) could predict 6-month (T3) global cognitive response to treatment better than any other memory or executive measure. Moreover, change in attention performance from baseline to 6 |
| 520 | |
▼a Conclusion: Our findings support our hypothesis that measures of attention under high-load conditions are sensitive to donepezil. Performance on these measures predicted long-term cognitive, functional, and behavioral response to ChEIs. |
| 590 | |
▼a School code: 0046. |
| 650 | 4 |
▼a Psychology. |
| 650 | 4 |
▼a Neurosciences. |
| 650 | 4 |
▼a Clinical psychology. |
| 690 | |
▼a 0621 |
| 690 | |
▼a 0317 |
| 690 | |
▼a 0622 |
| 710 | 20 |
▼a City University of New York.
▼b Psychology. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-12B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0046 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14999671
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자 |