| LDR | | 02244nmm uu200433 4500 |
| 001 | | 000000331032 |
| 005 | | 20240805163304 |
| 008 | | 181129s2018 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438128514 |
| 035 | |
▼a (MiAaPQ)AAI10831386 |
| 035 | |
▼a (MiAaPQ)grad.msu:16162 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 082 | 0 |
▼a 616 |
| 100 | 1 |
▼a Schroeder, Laura Elizabeth. |
| 245 | 10 |
▼a Assessing the Involvement of Altered Neurotensin Signaling in Anorexia Nervosa. |
| 260 | |
▼a [S.l.] :
▼b Michigan State University.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 308 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B. |
| 500 | |
▼a Advisers: Gina M. Leinninger |
| 502 | 1 |
▼a Thesis (Ph.D.)--Michigan State University, 2018. |
| 520 | |
▼a Assessing the Involvement of Altered Neurotensin Signaling in Anorexia Nervosa By Laura Elizabeth Schroeder Anorexia Nervosa (AN), characterized by a persistent and detrimental drive to lose weight via restriction of food intake and excessive ex |
| 520 | |
▼a In an effort to better understand the genetic basis of AN, recent work has been performed to uncover rare genetic variants that confer high risk of disease development. Loss-of-function variants in Neurotensin (Nts) and Nts Receptor 1 (NtsR1) we |
| 520 | |
▼a This hypothesis was explored via three different approaches. First, the location and density of Nts populations within the brains of Nts Cre |
| 520 | |
▼a Altogether, the data presented in this thesis highlight the possible genetic and neurocircuitry alterations to the Nts-NtsR1 system that may promote and/or be the result of development of AN. These data also indicate the need for future studies |
| 590 | |
▼a School code: 0128. |
| 650 | 4 |
▼a Neurosciences. |
| 650 | 4 |
▼a Cellular biology. |
| 690 | |
▼a 0317 |
| 690 | |
▼a 0379 |
| 710 | 20 |
▼a Michigan State University.
▼b Cell and Molecular Biology. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-11B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0128 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14999512
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자 |