| LDR | | 00000nmm u2200205 4500 |
| 001 | | 000000330840 |
| 005 | | 20241105132258 |
| 008 | | 181129s2018 ||| | | | eng d |
| 020 | |
▼a 9780438126244 |
| 035 | |
▼a (MiAaPQ)AAI10903018 |
| 035 | |
▼a (MiAaPQ)umichrackham:001299 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 049 | 1 |
▼f DP |
| 082 | 0 |
▼a 574 |
| 100 | 1 |
▼a Ma, Yiqin. |
| 245 | 10 |
▼a Chromatin Structure Changes During Terminal Differentiation and Cell Cycle Exit in Drosophila melanogaster. |
| 260 | |
▼a [S.l.] :
▼b University of Michigan.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 170 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B. |
| 500 | |
▼a Adviser: Laura Buttitta. |
| 502 | 1 |
▼a Thesis (Ph.D.)--University of Michigan, 2018. |
| 520 | |
▼a During development, the number of cell divisions must be precisely controlled in order to produce tissues of the correct shape, composition and size. The majority of cells complete their final cell cycle during a process called terminal differen |
| 520 | |
▼a To examine the relationship between cell cycle exit and chromatin structure during terminal differentiation, I characterized the temporal changes in chromatin accessibility and gene expression during the process of terminal differentiation in th |
| 520 | |
▼a Higher order chromatin organization such as the clustering of heterochromatin in the nucleus is also impacted by cell cycle exit and terminal differentiation. I found that heterochromatin clusters as cells exit the cell cycle and terminally diff |
| 590 | |
▼a School code: 0127. |
| 650 | 4 |
▼a Cellular biology. |
| 690 | |
▼a 0379 |
| 710 | 20 |
▼a University of Michigan.
▼b Molecular, Cellular, and Developmental Biology. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-12B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0127 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15000525
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자
▼b 관리자 |