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020 ▼a 9780438118621
035 ▼a (MiAaPQ)AAI10902600
035 ▼a (MiAaPQ)0799vireo:611Wee
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0491 ▼f DP
0820 ▼a 614
1001 ▼a Wee, Sang Ouk.
24510 ▼a Effect of Aerobic Exercise on Cerebral Blood Flow and Cognitive Function in Persons with Down Syndrome.
260 ▼a [S.l.] : ▼b University of Illinois at Chicago., ▼c 2017
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2017
300 ▼a 105 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
500 ▼a Adviser: Bo Fernhall.
5021 ▼a Thesis (Ph.D.)--University of Illinois at Chicago, 2017.
520 ▼a Down syndrome (DS), the leading genetic condition of intellectual disability, is associated with high risk of cognitive decline, dementia, and Alzheimer's disease (AD). Cognitive decline with dementia and AD hinders not only the wellbeing of ind
520 ▼a Exercise can improve cerebral blood flow and cognitive function in individuals without DS. However, it is unknown if the cerebral blood flow (CBF) characteristics are related to cognitive function in individuals with DS at rest and post exercise
520 ▼a Thus, we investigated the difference in cognitive function and CBF and its relationship in individuals with and without DS. We further investigated the effects of a single bout of moderate intensity aerobic exercise on cognitive function and CBF
520 ▼a Cognitive function was significantly lower (p<0.05) in individuals with DS and both the cerebral artery pulsatility index (PI) and resistance index (RI) were significantly higher in individuals with DS compared to controls (p<0.05 for all). Howe
520 ▼a Our data show that cognitive function was not related to CBF velocity. Moderate intensity exercise did not improve CBF velocity and cognitive function in individuals with DS, whereas individuals without DS showed significant cognitive function i
590 ▼a School code: 0799.
650 4 ▼a Health sciences.
690 ▼a 0566
71020 ▼a University of Illinois at Chicago. ▼b Applied Health Science.
7730 ▼t Dissertation Abstracts International ▼g 79-10B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0799
791 ▼a Ph.D.
792 ▼a 2017
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15000375 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자 ▼b 관리자