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020 ▼a 9780438098114
035 ▼a (MiAaPQ)AAI10901870
035 ▼a (MiAaPQ)OhioLINK:osu1511979972361293
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0491 ▼f DP
0820 ▼a 616
1001 ▼a Russell, Luke.
24510 ▼a Oncolytic Virus Expression of PTENalpha Directs Antitumor Immune Response.
260 ▼a [S.l.] : ▼b The Ohio State University., ▼c 2017
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2017
300 ▼a 109 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
500 ▼a Adviser: Balveen Kaur.
5021 ▼a Thesis (Ph.D.)--The Ohio State University, 2017.
520 ▼a Brain tumors affect over 680,000 people in the USA, with malignant brain tumors accounting for approximately 20% of these patients. Malignant brain tumors are among the most aggressive and deadly tumors, and can be divided to primary tumors that
520 ▼a Brain tumor treatment continues to be a major challenge in oncology. The standard of care for brain tumors consists of maximal surgical resection followed by radiotherapy and chemotherapy. However, despite continued research and new approaches f
520 ▼a Oncolytic viral therapy is a promising novel therapy for brain tumors which recently gained FDA approval for the treatment of metastatic melanoma, and is in clinical trials for a variety of tumor indications, including brain tumors. Here we gene
590 ▼a School code: 0168.
650 4 ▼a Neurosciences.
690 ▼a 0317
71020 ▼a The Ohio State University. ▼b Neuroscience Graduate Studies Program.
7730 ▼t Dissertation Abstracts International ▼g 79-12B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0168
791 ▼a Ph.D.
792 ▼a 2017
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15000300 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자 ▼b 관리자