| LDR | | 00000nmm u2200205 4500 |
| 001 | | 000000330621 |
| 005 | | 20241101170450 |
| 008 | | 181129s2017 ||| | | | eng d |
| 020 | |
▼a 9780438091641 |
| 035 | |
▼a (MiAaPQ)AAI10871386 |
| 035 | |
▼a (MiAaPQ)OhioLINK:osu1482945107612275 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 049 | 1 |
▼f DP |
| 082 | 0 |
▼a 610 |
| 100 | 1 |
▼a Agarwal, Pranay. |
| 245 | 10 |
▼a Multiscale Biomaterials for Cell and Tissue Engineering. |
| 260 | |
▼a [S.l.] :
▼b The Ohio State University.,
▼c 2017 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2017 |
| 300 | |
▼a 182 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B. |
| 500 | |
▼a Adviser: Xiaoming He. |
| 502 | 1 |
▼a Thesis (Ph.D.)--The Ohio State University, 2017. |
| 520 | |
▼a The aim of tissue engineering is to fabricate functional tissue constructs for treating diseases. Contemporary approach for tissue engineering is to embed cells in homogenous three-dimensional (3D) macroscopic scaffolds for mimicking the functio |
| 520 | |
▼a First, the development of a novel non-planar microfluidic flow-focusing device for high-throughput encapsulation of mouse embryonic stem cells (mESCs) in a liquid core of microcapsules with an alginate hydrogel shell is reported. Using the non-p |
| 520 | |
▼a Next, a bottom-up approach for fabricating 3D vascularized human breast tumor model with the core-shell microencapsulation technology is developed. Microtumors (i.e., 3D aggregates of cancer cells) are generated in core-shell microcapsules and u |
| 520 | |
▼a To conclude, this dissertation work demonstrates how microscale encapsulation of cells via microfluidics provides a powerful suite of tools to engineering the cellular microenvironment at micro and macro scales. The technologies and systems desc |
| 590 | |
▼a School code: 0168. |
| 650 | 4 |
▼a Biomedical engineering. |
| 650 | 4 |
▼a Medicine. |
| 690 | |
▼a 0541 |
| 690 | |
▼a 0564 |
| 710 | 20 |
▼a The Ohio State University.
▼b Biomedical Engineering. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-10B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0168 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2017 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15000225
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자
▼b 관리자 |