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020 ▼a 9780438091214
035 ▼a (MiAaPQ)AAI10871341
035 ▼a (MiAaPQ)OhioLINK:osu1460981460
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 614.4
1001 ▼a Maharry, Kati S.
24510 ▼a Risk Factors for Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma Incidence in Postmenopausal Women: A Women's Health Initiative (WHI) Study.
260 ▼a [S.l.] : ▼b The Ohio State University., ▼c 2016
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2016
300 ▼a 214 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
500 ▼a Adviser: Electra Paskett.
5021 ▼a Thesis (Ph.D.)--The Ohio State University, 2016.
520 ▼a Various exposures have been investigated by epidemiologic studies as risk factors for leukemia incidence, however studies focusing on and therefore findings particular to Small Lymphocytic Lymphoma (SLL) and Chronic Lymphocytic Leukemia (CLL) ha
520 ▼a Using the Women's Health Initiative (WHI) and applying an age and race matched, nested, 1:4 case-control design, we investigated CLL/SLL risk in postmenopausal women with three specific aims of interest: personal habits, comprising diet, drinkin
520 ▼a Women enrolled on WHI clinical trials who consumed coffee on a regular basis had lower risk of CLL/SLL (odds ratio (OR) = 0.73, 95% confidence interval (CI): 0.51, 1.05
520 ▼a Overall, we can conclude that risk factors which matter the most for CLL/SLL risk, such as coffee drinking, obesity, and OC use, all have estrogenic effects which in this case appear to offer protection. The biological mechanisms leading to thes
520 ▼a Our findings identified risk factors specific to industrialized countries helping explain the higher CLL/SLL incidence in these countries, compared to developing countries. In addition, we showed a probable association of estrogen dominance bein
590 ▼a School code: 0168.
650 4 ▼a Epidemiology.
690 ▼a 0766
71020 ▼a The Ohio State University. ▼b Public Health.
7730 ▼t Dissertation Abstracts International ▼g 79-10B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0168
791 ▼a Ph.D.
792 ▼a 2016
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15000208 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자