LDR | | 00000nmm u2200205 4500 |
001 | | 000000330595 |
005 | | 20241101150722 |
008 | | 181129s2017 ||| | | | eng d |
020 | |
▼a 9780438091061 |
035 | |
▼a (MiAaPQ)AAI10871326 |
035 | |
▼a (MiAaPQ)OhioLINK:ucin1491316295006087 |
040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
049 | 1 |
▼f DP |
082 | 0 |
▼a 615 |
100 | 1 |
▼a Intarakumhaeng, Rattikorn. |
245 | 10 |
▼a Factors Influencing Percutaneous Absorption: Effects of Solvents, Solute Physicochemical Properties, and Penetration Enhancer. |
260 | |
▼a [S.l.] :
▼b University of Cincinnati.,
▼c 2017 |
260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2017 |
300 | |
▼a 197 p. |
500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B. |
502 | 1 |
▼a Thesis (Ph.D.)--University of Cincinnati, 2017. |
520 | |
▼a Skin has been the focus of research as a site of local and systemic drug delivery due to its advantages over other routes of drug delivery. However, the determining factors that could affect the transport of compounds through and into the skin a |
520 | |
▼a The objective of Chapter 3 was to examine the effects of solvents upon the deposition of a model solute, corticosterone (CS) in the stratum corneum (SC) that could influence skin absorption of the solute after topical application. The solvents u |
520 | |
▼a The study performed in Chapter 4 was a continuing effort to investigate the effects of solvents on skin absorption of lipophilic and polar solutes and examine the relationships between solute physicochemical properties and skin absorption of the |
520 | |
▼a In Chapter 5, we probed the mechanism of the observed high finite dose skin permeation of urea, in contrast to its permeability coefficient. A small hydrophilic solute ethylene glycol (EG) with molecular weight similar to urea was studied for co |
520 | |
▼a Chapter 6 aimed to examine the skin penetration of petrolatum and soybean oil after skin application with and without a penetration enhancer, glyceryl monooleate (GlyMOle). GlyMOle was found to enhance the penetration of petrolatum into the spli |
590 | |
▼a School code: 0045. |
650 | 4 |
▼a Pharmaceutical sciences. |
690 | |
▼a 0572 |
710 | 20 |
▼a University of Cincinnati.
▼b Pharmacy: Pharmaceutical Sciences/Biopharmaceutics. |
773 | 0 |
▼t Dissertation Abstracts International
▼g 79-10B(E). |
773 | |
▼t Dissertation Abstract International |
790 | |
▼a 0045 |
791 | |
▼a Ph.D. |
792 | |
▼a 2017 |
793 | |
▼a English |
856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15000199
▼n KERIS |
980 | |
▼a 201812
▼f 2019 |
990 | |
▼a 관리자
▼b 관리자 |