| LDR | | 00000nmm u2200205 4500 |
| 001 | | 000000330228 |
| 005 | | 20241025144601 |
| 008 | | 181129s2018 ||| | | | eng d |
| 020 | |
▼a 9780438002296 |
| 035 | |
▼a (MiAaPQ)AAI10825384 |
| 035 | |
▼a (MiAaPQ)ucla:16784 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 049 | 1 |
▼f DP |
| 082 | 0 |
▼a 616 |
| 100 | 1 |
▼a O'Connell, Dylan Patrick. |
| 245 | 10 |
▼a Development, Validation, and Translation of a Respiratory Motion Model-Based 4DCT Technique for Use as a Clinical Protocol for Radiation Therapy Treatment Planning. |
| 260 | |
▼a [S.l.] :
▼b University of California, Los Angeles.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 143 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B. |
| 500 | |
▼a Adviser: Daniel A. Low. |
| 502 | 1 |
▼a Thesis (Ph.D.)--University of California, Los Angeles, 2018. |
| 520 | |
▼a Breathing motion in radiotherapy is commonly managed with four-dimensional computed tomography (4DCT). 4DCT datasets consist of multiple breathing-gated images that display motion of the subject's anatomy over a breathing period. Commercial 4DCT |
| 520 | |
▼a A validation study was conducted involving comparing 5DCT images to commercial 4DCT using an animal model. Reproducible and periodic breathing patterns were achieved through mechanical ventilation and image similarity was quantified using landma |
| 520 | |
▼a Differences in measured tumor motion between 5DCT and commercial 4DCT were examined in a cohort of 20 lung cancer patients. Solutions for the unique challenges of using model model-based techniques clinically, such as appropriate amplitude inter |
| 520 | |
▼a A quality management program was developed to ensure the safety of the protocol using risk analysis methods such as process mapping and failure modes and effects analysis. In addition, safety of the in-house software required to implement the te |
| 520 | |
▼a The physiological significance of the 5D model parameters was investigated, particularly their dependence on breathing rate during acquisition. It was shown that the model parameter relating tissue motion to breathing amplitude was largely invar |
| 520 | |
▼a A prospective scanning method was developed to reduce the number of fast helical scans, and associated imaging dose, necessary to perform 5DCT while maintaining motion modeling accuracy. A simulation study was conducted using patient breathing t |
| 590 | |
▼a School code: 0031. |
| 650 | 4 |
▼a Medical imaging. |
| 690 | |
▼a 0574 |
| 710 | 20 |
▼a University of California, Los Angeles.
▼b Biomedical Physics. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-10B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0031 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14998761
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자
▼b 관리자 |