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020 ▼a 9780355460339
035 ▼a (MiAaPQ)AAI10708561
035 ▼a (MiAaPQ)0799vireo:475Hedlund
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0491 ▼f DP
0820 ▼a 614
1001 ▼a Hedlund, Nancy.
24510 ▼a Impact of Drug Shortages on Patient Treatment and Survival: The Case of Cytarabine and AML Leukemia.
260 ▼a [S.l.] : ▼b University of Illinois at Chicago., ▼c 2017
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2017
300 ▼a 351 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-05(E), Section: B.
500 ▼a Adviser: Lisa Powell.
5021 ▼a Thesis (Ph.D.)--University of Illinois at Chicago, 2017.
506 ▼a This item is not available from ProQuest Dissertations & Theses.
520 ▼a Introduction: Drug shortages of parenteral injectable medications reached an all time high in calendar year 2011. The focus of this research is to understand implications of a shortage of the chemotherapy drug cytarabine, for which there is no
520 ▼a Methods: The study population is patients presenting with an Acute Myelogenous Leukemia diagnosis (AML) between December 2010 and October 2011, during which the FDA determined the cytarabine drug supply to be compromised. Primary data sources w
520 ▼a Results: Odds for receipt of treatment within 14 days of diagnosis for persons diagnosed during a period of major shortage was reduced by almost 50% (OR=0.537, p < 0.05). Median days to first qualifying dose inpatient chemotherapy jumped from 7
520 ▼a Conclusion: Diagnosis during a period of major shortage was associated with reduced probability and prolonged time to treatment and a higher hazard for early death. Further study of imbalance between current market price and pharmaceutical manu
590 ▼a School code: 0799.
650 4 ▼a Public health.
650 4 ▼a Economics.
650 4 ▼a Medicine.
690 ▼a 0573
690 ▼a 0501
690 ▼a 0564
71020 ▼a University of Illinois at Chicago. ▼b Health Policy and Administration.
7730 ▼t Dissertation Abstracts International ▼g 79-05B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0799
791 ▼a Ph.D.
792 ▼a 2017
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T14996793 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자 ▼b 관리자