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020 ▼a 9780438035812
035 ▼a (MiAaPQ)AAI10744313
035 ▼a (MiAaPQ)upenngdas:13109
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0491 ▼f DP
0820 ▼a 610
1001 ▼a Ginart, Paul.
24510 ▼a Visualizing Allele Specific Expression in Single Cells.
260 ▼a [S.l.] : ▼b University of Pennsylvania., ▼c 2018
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2018
300 ▼a 132 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
500 ▼a Adviser: Arjun Raj.
5021 ▼a Thesis (Ph.D.)--University of Pennsylvania, 2018.
520 ▼a Single molecule RNA FISH techniques have enabled the quantification of gene expression at the single cell level, revealing significant variability that has been previously obscured by techniques measuring population averages. These techniques, h
520 ▼a We then leverage SNP-FISH in the study of imprinting dysregulation. Humans with imprinting disorders have been known to present with highly variable phenotypic severity, and it was thought that these diferences might arise at the single-cell lev
590 ▼a School code: 0175.
650 4 ▼a Bioengineering.
690 ▼a 0202
71020 ▼a University of Pennsylvania. ▼b Bioengineering.
7730 ▼t Dissertation Abstracts International ▼g 79-10B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0175
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T14996828 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자 ▼b 관리자