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008181129s2017 ||| | | | eng d
020 ▼a 9780355597882
035 ▼a (MiAaPQ)AAI10688516
035 ▼a (MiAaPQ)washington:18192
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0491 ▼f DP
0820 ▼a 574
1001 ▼a Curran, Elizabeth C.
24510 ▼a Discovery of Novel TAF1 DNA Binding Domains in TFIID Promoter Recognition and Gene Transcription.
260 ▼a [S.l.] : ▼b University of Washington., ▼c 2017
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2017
300 ▼a 108 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-05(E), Section: B.
500 ▼a Advisers: Edith Wang
5021 ▼a Thesis (Ph.D.)--University of Washington, 2017.
506 ▼a This item is not available from ProQuest Dissertations & Theses.
520 ▼a The central dogma of biology describes the basic flow of genetic information starting from DNA, which is converted to message RNA, then into functional proteins. This classical view provides a framework for how a cell can respond to its environm
520 ▼a Presented here is the discovery of two DNA binding domains (DBDs) in TAF1, the largest TFIID subunit. This work identified and characterized two previously unknown DBDs, the winged helix (WH) located in the central DUF3591 domain and the evoluti
590 ▼a School code: 0250.
650 4 ▼a Molecular biology.
650 4 ▼a Pharmacology.
690 ▼a 0307
690 ▼a 0419
71020 ▼a University of Washington. ▼b Pharmacology.
7730 ▼t Dissertation Abstracts International ▼g 79-05B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0250
791 ▼a Ph.D.
792 ▼a 2017
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T14996765 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자 ▼b 관리자