| LDR | | 00000nmm u2200205 4500 |
| 001 | | 000000329986 |
| 005 | | 20241017161251 |
| 008 | | 181129s2017 ||| | | | eng d |
| 020 | |
▼a 9780355629057 |
| 035 | |
▼a (MiAaPQ)AAI10641431 |
| 035 | |
▼a (MiAaPQ)umd:18580 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 049 | 1 |
▼f DP |
| 082 | 0 |
▼a 574.191 |
| 100 | 1 |
▼a Goldtzvik, Yonathan.
▼0 (orcid)0000-0003-1261-9858 |
| 245 | 10 |
▼a Understanding the Motility of Molecular Motors Using Theory and Simulations. |
| 260 | |
▼a [S.l.] :
▼b University of Maryland, College Park.,
▼c 2017 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2017 |
| 300 | |
▼a 160 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-07(E), Section: B. |
| 500 | |
▼a Adviser: Devarajan Thirumalai. |
| 502 | 1 |
▼a Thesis (Ph.D.)--University of Maryland, College Park, 2017. |
| 506 | |
▼a This item is not available from ProQuest Dissertations & Theses. |
| 520 | |
▼a Molecular motors are indispensable machines that are in charge of transporting cargoes within living cells. Despite recent advances in the study of these molecules, there is much that we still do not understand regarding the underlying mechanism |
| 520 | |
▼a Dynein is a large motor that transports cargo along microtubules towards their negative pole. Unlike other motors, such as conventional kinesin, the motility of dynein is highly stochastic. We developed a novel theoretical approach, which reprod |
| 520 | |
▼a A less understood aspect of dynein is the complex set of allosteric transitions in response to ATP binding and hydrolysis, and microtubule binding. The resulting conformational transitions propel the motor forward to the minus end of the microtu |
| 520 | |
▼a Kinesins are highly processive motor proteins that transport cargo along microtubules toward their positive poles. Experiments show that the kinesin motor domains propel the motor forward by passing each other in a hand-over-hand motion. However |
| 590 | |
▼a School code: 0117. |
| 650 | 4 |
▼a Biophysics. |
| 650 | 4 |
▼a Biology. |
| 650 | 4 |
▼a Molecular physics. |
| 690 | |
▼a 0786 |
| 690 | |
▼a 0306 |
| 690 | |
▼a 0609 |
| 710 | 20 |
▼a University of Maryland, College Park.
▼b Biophysics. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-07B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0117 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2017 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14996697
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자
▼b 관리자 |