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020 ▼z 9780309090889
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24500 ▼a Review of U.S. EPA's ORD staff handbook for developing IRIS assessments : ▼b 2020 version / ▼c Committee to Review EPA'S IRIS Assessment Handbook, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies. ▼h [electronic resource]
264 1 ▼a Washington, DC : ▼b National Academies Press, ▼c [2022]
300 ▼a 1 online resource (1 PDF file (xii, 97 pages)) : ▼b illustrations.
336 ▼a text ▼b txt ▼2 rdacontent
337 ▼a computer ▼b c ▼2 rdamedia
338 ▼a online resource ▼b cr ▼2 rdacarrier
4901 ▼a Consensus study report of the National Academies of Sciences, Engineering, Medicine
504 ▼a Includes bibliographical references.
5203 ▼a The U.S. Environmental Protection Agency's (EPA) Integrated Risk Information System (IRIS) program develops human health assessments that focus on hazard identification and dose-response analyses for chemicals in the environment. The ORD Staff Handbook for Developing IRIS Assessments (the handbook) provides guidance to scientists who perform the IRIS assessments in order to foster consistency in the assessments and enhance transparency about the IRIS assessment process. At the request of the EPA, this report reviews the procedures and considerations for operationalizing the principles of systematic reviews and the methods described in the handbook for determining the scope of the IRIS assessments, evidence integration, extrapolation techniques, dose-response analyses, and characterization of uncertainties.
536 ▼a This activity was supported by Contract No. 68HERC19D0011 between the National Academy of Sciences and the U. S. Environmental Protection Agency. Any opinions, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect the views of any organization or agency that provided support for the project.
588 ▼a Description based on online resource; title from PDF title page (viewed December 13, 2022).
590 ▼a WorldCat record variable field(s) change: 050, 082, 610, 650
61010 ▼a United States. ▼b Environmental Protection Agency. ▼b Office of Research and Development.
61012 ▼a United States. ▼b Environmental Protection Agency. ▼b Office of Research and Development.
650 0 ▼a Risk assessment.
65012 ▼a Environmental Exposure.
65012 ▼a Information Systems ▼x organization & administration.
65022 ▼a Risk Assessment.
65022 ▼a Program Evaluation.
65022 ▼a United States Government Agencies.
651 2 ▼a United States.
655 2 ▼a Review.
7102 ▼a National Academies of Sciences, Engineering, and Medicine (U.S.). ▼b Committee to Review EPA'S IRIS Assessment Handbook, ▼e issuing body.
77608 ▼i Print version: ▼a National Academies of Sciences, Engineering, and Medicine ▼t Review of U. S. EPA's ORD Staff Handbook for Developing IRIS Assessments ▼d Washington, D.C. : National Academies Press,c2022 ▼z 9780309090889
830 0 ▼a Consensus study report.
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990 ▼a 관리자
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