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019 ▼a 1135668643 ▼a 1144317751 ▼a 1157119687 ▼a 1168139842
020 ▼a 0691186081 ▼q (electronic bk.)
020 ▼a 9780691186085 ▼q (electronic bk.)
020 ▼z 0691163847
020 ▼z 9780691163840
0247 ▼a 10.1515/9780691186085. ▼2 doi
035 ▼a 2258675 ▼b (N$T)
035 ▼a (OCoLC)1166436269 ▼z (OCoLC)1135668643 ▼z (OCoLC)1144317751 ▼z (OCoLC)1157119687 ▼z (OCoLC)1168139842
037 ▼a EBA-DEGRUYTER2020
040 ▼a BRF ▼b eng ▼e rda ▼e rda ▼c BRF ▼d MM9 ▼d EBLCP ▼d DEGRU ▼d JSTOR ▼d UKAHL ▼d TOH ▼d TEFOD ▼d N$T ▼d YDX ▼d BRX ▼d OCLCF ▼d IU0 ▼d ANV ▼d 248032
044 ▼a nju ▼c US-NJ
049 ▼a MAIN
050 4 ▼a RC263 ▼b .A447 2020
060 4 ▼a QZ 200
072 7 ▼a MED062000. ▼2 bisacsh
08204 ▼a 616.994 ▼2 23
1001 ▼a Aktipis, Athena, ▼e author. ▼4 aut ▼4 http://id.loc.gov/vocabulary/relators/aut
24514 ▼a The Cheating Cell : ▼b How Evolution Helps Us Understand and Treat Cancer / ▼c Athena Aktipis.
260 ▼a Princeton, NJ : ▼b Princeton University Press, ▼c [2020]
300 ▼a 1 online resource (256 pages) : ▼b 19 b/w illus.
336 ▼a text ▼2 rdacontent
337 ▼a computer ▼2 rdamedia
338 ▼a online resource ▼2 rdacarrier
347 ▼a text file ▼b PDF ▼2 rda
504 ▼a Includes bibliographical references and index.
50500 ▼t Frontmatter -- ▼t CONTENTS -- ▼t Acknowledgments -- ▼t 1. Introduction: Evolution in the Flesh -- ▼t 2. Why Does Cancer Evolve? -- ▼t 3. Cheating in Multicellular Cooperation -- ▼t 4. Cancer from Womb to Tomb -- ▼t 5. Cancer across the Tree of Life -- ▼t 6. The Hidden World of Cancer Cells -- ▼t 7. How to Control Cancer -- ▼t Notes -- ▼t Bibliography -- ▼t Index
520 ▼a A fundamental and groundbreaking reassessment of how we view and manage cancer When we think of the forces driving cancer, we don't necessarily think of evolution. But evolution and cancer are closely linked, for the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer's evolutionary origins, researchers can come up with more effective, revolutionary treatments. Athena Aktipis goes back billions of years to explore when unicellular forms became multicellular organisms. Within these bodies of cooperating cells, cheating ones arose, overusing resources and replicating out of control, giving rise to cancer. Aktipis illustrates how evolution has paved the way for cancer's ubiquity, and why it will exist as long as multicellular life does. Even so, she argues, this doesn't mean we should give up on treating cancer-in fact evolutionary approaches offer new and promising options for the disease's prevention and treatments that aim at long-term management rather than simple eradication. Looking across species-from sponges and cacti to dogs and elephants-we are discovering new mechanisms of tumor suppression and the many ways that multicellular life-forms have evolved to keep cancer under control. By accepting that cancer is a part of our biological past, present, and future-and that we cannot win a war against evolution-treatments can become smarter, more strategic, and more humane. Unifying the latest research from biology, ecology, medicine, and social science, The Cheating Cell challenges us to rethink cancer's fundamental nature and our relationship to it.
546 ▼a In English.
5550 ▼a Available in electronic full text to members of the University via the Library web catalogue.
5880 ▼a Description based on online resource; title from PDF title page (publisher's Web site, viewed 29. Feb 2020).
590 ▼a OCLC control number change
650 4 ▼a Adaptive oncogenesis.
650 4 ▼a evolution.
650 4 ▼a immunology.
650 4 ▼a oncology.
650 7 ▼a MEDICAL / Oncology. ▼2 bisacsh
650 0 ▼a Cancer ▼v Popular works.
650 0 ▼a Cancer cells.
650 0 ▼a Evolution (Biology)
650 2 ▼a Neoplasms. ▼0 (DNLM)D009369
650 7 ▼a Cancer. ▼2 fast ▼0 (OCoLC)fst00845317
650 7 ▼a Cancer cells. ▼2 fast ▼0 (OCoLC)fst00845563
650 7 ▼a Evolution (Biology) ▼2 fast ▼0 (OCoLC)fst00917302
655 4 ▼a Electronic books.
655 7 ▼a Popular works. ▼2 fast ▼0 (OCoLC)fst01423846
77608 ▼c Original ▼z 0691163847 ▼z 9780691163840. ▼w (OCoLC)1119533391
85640 ▼3 EBSCOhost ▼u http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=2258675
938 ▼a Askews and Holts Library Services ▼b ASKH ▼n AH37096407
938 ▼a De Gruyter ▼b DEGR ▼n 9780691186085
938 ▼a ProQuest Ebook Central ▼b EBLB ▼n EBL6005043
938 ▼a EBSCOhost ▼b EBSC ▼n 2258675
938 ▼a YBP Library Services ▼b YANK ▼n 16497359
990 ▼a 관리자
994 ▼a 92 ▼b N$T