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008150423s2015 dcua ob 000 0 eng d
020 ▼a 9780309367844 ▼q electronic bk.
020 ▼a 0309367840 ▼q electronic bk.
020 ▼z 9780309367837 ▼q paperback
020 ▼z 0309367832 ▼q paperback
035 ▼a (OCoLC)907932833
040 ▼a MMU ▼b eng ▼e rda ▼c MMU ▼d CUS ▼d N$T ▼d 248032
043 ▼a n-us---
049 ▼a K4RA
050 4 ▼a RA650.5 ▼b .P68 2015
072 7 ▼a MED ▼x 030000 ▼2 bisacsh
072 7 ▼a MED ▼x 076000 ▼2 bisacsh
072 7 ▼a MED ▼x 078000 ▼2 bisacsh
08204 ▼a 614.4273 ▼2 23
1001 ▼a Sharples, Frances Ellen, ▼e author.
24510 ▼a Potential risks and benefits of gain-of-function research : ▼b summary of workshop / ▼c Frances Sharples, Jo Husbands, Anne-Marie Mazza, Audrey Thevenon, and India Hook-Barnard, Rapporteurs ; Board on Life Sciences, Division on Earth and Life Studies, Committee on Science, Technology, and Law, Policy and Global Affairs Division, Board on Health Sciences Policy, Institute of Medicine, National Research Council and Institute of Medicine of National Academies.
264 1 ▼a Washington, D.C. : ▼b The National Academies Press, ▼c [2015]
300 ▼a 1 online resource (xiv, 125 pages) : ▼b color illustrations
336 ▼a text ▼b txt ▼2 rdacontent
337 ▼a computer ▼b c ▼2 rdamedia
338 ▼a online resource ▼b cr ▼2 rdacarrier
504 ▼a Includes bibliographical references.
5050 ▼a Introduction -- Assessing risks and benefits -- Gain-of-function research: background and alternatives -- Potential benefits of gain-of-function research -- Potential risks: biosafety and biosecurity -- Policy implications -- Key issues for risk/benefit assessment for gain-of-function research.
520 ▼a "On October 17, 2014, spurred by incidents at U.S. government laboratories that raised serious biosafety concerns, the United States government launched a one-year deliberative process to address the continuing controversy surrounding so-called "gain-of-function" (GOF) research on respiratory pathogens with pandemic potential. The gain of function controversy began in late 2011 with the question of whether to publish the results of two experiments involving H5N1 avian influenza and continued to focus on certain research with highly pathogenic avian influenza over the next three years. The heart of the U.S. process is an evaluation of the potential risks and benefits of certain types of GOF experiments with influenza, SARS, and MERS viruses that would inform the development and adoption of a new U.S. Government policy governing the funding and conduct of GOF research. Potential Risks and Benefits of Gain-of-Function Research is the summary of a two-day public symposia on GOF research. Convened in December 2014 by the Institute of Medicine and the National Research Council, the main focus of this event was to discuss principles important for, and key considerations in, the design of risk and benefit assessments of GOF research. Participants examined the underlying scientific and technical questions that are the source of current discussion and debate over GOF research involving pathogens with pandemic potential. This report is a record of the presentations and discussion of the meeting."
5880 ▼a Online resource; title from PDF title page (EBSCO, viewed May 13, 2015)
650 0 ▼a Epidemics ▼z United States ▼x Prevention ▼v Congresses.
650 7 ▼a MEDICAL / Forensic Medicine. ▼2 bisacsh
650 7 ▼a MEDICAL / Preventive Medicine. ▼2 bisacsh
650 7 ▼a MEDICAL / Public Health. ▼2 bisacsh
655 4 ▼a Electronic books.
7001 ▼a Mazza, Anne-Marie, ▼e author.
7001 ▼a Thevenon, Audrey, ▼e author.
7001 ▼a Hook-Barnard, India, ▼e author.
7102 ▼a Institute of Medicine (U.S.). ▼b Board on Health Sciences Policy, ▼e issuing body.
7102 ▼a National Research Council (U.S.). ▼b Board on Life Sciences, ▼e issuing body.
7102 ▼a National Research Council (U.S.). ▼b Committee on Science, Technology, and Law, ▼e issuing body.
85640 ▼3 EBSCOhost ▼u http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=991107
938 ▼a EBSCOhost ▼b EBSC ▼n 991107
990 ▼a 관리자