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020 ▼a 9780309298155 ▼q electronic bk.
020 ▼a 0309298156 ▼q electronic bk.
020 ▼z 9780309298148
020 ▼z 0309298148
035 ▼a (OCoLC)877436043
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24500 ▼a Technological challenges in antibiotic discovery and development ▼h [electronic resource] : ▼b a workshop summary / ▼c Douglas Friedman and Joe Alper, Rapporteurs Chemical Sciences Roundtable Board on Chemical Sciences and Technology : Division on Earth and Life Studies.
264 1 ▼a Washington, District of Columbia : ▼b National Academies Press, ▼c 2014.
264 4 ▼c 짤2014
300 ▼a 1 online resource (48 pages) : ▼b illustrations (some color), tables.
336 ▼a text ▼2 rdacontent
337 ▼a computer ▼2 rdamedia
338 ▼a online resource ▼2 rdacarrier
504 ▼a Includes bibliographical references.
5208 ▼a Technological Challenges in Antibiotic Discovery and Development is the summary of a workshop convened by the Chemical Sciences Roundtable in September 2013 to explore the current state of antibiotic discovery and examine the technology available to facilitate development. Through formal presentations and panel discussions, participants from academia, industry, federal research agencies discussed the technical challenges present and the incentives and disincentives industry faces in antibiotic development, and identified novel approaches to antibiotic discovery. Antibiotic resistance is a serious and growing problem in modern medicine and it is emerging as a pre-eminent public health threat. Each year in the United States alone, at least two million acquire serious infections with bacteria that are resistant to one or more antibiotics, and at least 23,000 people die annually as a direct result of these antibiotic-resistant infections. In addition to the toll on human life, antibiotic-resistant infections add considerable and avoidable costs to the already overburdened U.S. health care system. This report explores the challenges in overcoming antibiotic resistance, screening for new antibiotics, and delivering them to the sites of infection in the body. The report also discusses a path forward to develop the next generation of potent antimicrobial compounds capable of once again tilting the battle against microbial pathogens in favor of humans. Technological Challenges in Antibiotic Discovery and Development gives a broad view of the landscape of antibiotic development and the technological challenges and barriers to be overcome.
588 ▼a Description based on online resource; title from PDF title page (ebrary, viewed May 4, 2014).
650 0 ▼a Drug resistance in microorganisms ▼v Congresses.
650 0 ▼a Public health ▼v Congresses.
650 0 ▼a Antibiotics ▼x Research ▼v Congresses.
650 7 ▼a HEALTH & FITNESS / Diseases / General. ▼2 bisacsh
650 7 ▼a MEDICAL / Clinical Medicine. ▼2 bisacsh
650 7 ▼a MEDICAL / Diseases. ▼2 bisacsh
650 7 ▼a MEDICAL / Evidence-Based Medicine. ▼2 bisacsh
650 7 ▼a MEDICAL / Internal Medicine. ▼2 bisacsh
650 7 ▼a Antibiotics ▼x Research. ▼2 fast ▼0 (OCoLC)fst00810432
650 7 ▼a Drug resistance in microorganisms. ▼2 fast ▼0 (OCoLC)fst00898704
650 7 ▼a Public health. ▼2 fast ▼0 (OCoLC)fst01082238
655 4 ▼a Electronic books.
655 7 ▼a Conference proceedings. ▼2 fast ▼0 (OCoLC)fst01423772
7001 ▼a Friedman, Douglas, ▼e speaker.
7001 ▼a Alper, Joe, ▼e speaker.
7102 ▼a National Research Council (U.S.)
77608 ▼i Print version: ▼t Technological challenges in antibiotic discovery and development : a workshop summary. ▼d Washington, District of Columbia : National Academies Press, c2014 ▼h xiii, 34 pages ▼z 9780309298148
85640 ▼3 EBSCOhost ▼u http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=867584
938 ▼a ebrary ▼b EBRY ▼n ebr10863893
938 ▼a EBSCOhost ▼b EBSC ▼n 867584
938 ▼a YBP Library Services ▼b YANK ▼n 11864925
990 ▼a 관리자