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020 ▼a 9780309306676 ▼q electronic bk.
020 ▼a 0309306671 ▼q electronic bk.
020 ▼z 9780309306669 (paperback)
020 ▼z 0309306663 (paperback)
035 ▼a (OCoLC)883575949
040 ▼a COO ▼b eng ▼e rda ▼c COO ▼d MMU ▼d CUS ▼d N$T ▼d YDXCP ▼d OCLCF ▼d 248032
043 ▼a n-us---
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050 4 ▼a R853.H8 ▼b C66 2014
060 4 ▼a W 20.55.H9
072 7 ▼a BUS ▼x 008000 ▼2 bisacsh
082 4 ▼a 174.28 ▼b 23
1112 ▼a Contemporary Issues in Human Subjects Protections (Workshop) ▼d (2014 : ▼c Washington, D.C.), ▼j author.
24510 ▼a Contemporary issues for protecting patients in cancer research : ▼b workshop summary / ▼c Sharyl J. Nass and Margie Patlak, rapporteurs; National Cancer Policy Forum, Board on Health Care Services, Institute of Medicine of the National Academies.
24630 ▼a Protecting patients in cancer research
264 1 ▼a Washington, D.C. : ▼b National Academies Press, ▼c [2014]
264 4 ▼c 짤2014
300 ▼a 1 online resource (xvii, 74 pages) : ▼b illustrations
336 ▼a text ▼b txt ▼2 rdacontent
337 ▼a computer ▼b c ▼2 rdamedia
338 ▼a online resource ▼b cr ▼2 rdacarrier
504 ▼a Includes bibliographical references.
5050 ▼a Introduction -- Current regulatory arena -- Common rule and HIPAA -- Shortcomings of current regulations and guidances -- Context -- Data deindentification -- Impediment to quality improvement and learning -- Varied interpretation -- Misaligned incentives -- Lack of harmonization with international standards -- Informed consent forms -- Informed consent process -- Consent tools -- Beyond consent -- HITECH -- Advanced notice of proposed rulemaking -- Patient perspectives on research protections -- Ethical challenges of genetic advances -- Patient consent for use of archived biospecimens -- Return of research results -- Clinically actionable findings -- Context matters -- Who pays -- Biospecimens from deceased participants -- The changing context of research and care -- Oversight in a learning health care system -- Oversight of pragmatic trials -- Multisite studies and IRB review -- Central IRBs -- New England Reliance Agreement -- Value of local IRBs -- Educational needs -- Research needs -- Wrap-up.
520 ▼a "In the nearly 40 years since implementation of federal regulations governing the protection of human participants in research, the number of clinical studies has grown exponentially. These studies have become more complex, with multisite trials now common, and there is increasing use of archived biospecimens and related data, including genomics data. In addition, growing emphasis on targeted cancer therapies requires greater collaboration and sharing of research data to ensure that rare patient subsets are adequately represented. Electronic records enable more extensive data collection and mining, but also raise concerns about the potential for inappropriate or unauthorized use of data, bringing patient protections into a new landscape. There are also long-standing concerns about the processes and forms used to obtain informed consent from patients participating in clinical studies. These changes and challenges raise new ethical and practical questions for the oversight of clinical studies, and for protecting patients and their health information in an efficient manner that does not compromise the progress of biomedical research. Contemporary Issues for Protecting Patients in Cancer Research is the summary of a workshop convened by the National Cancer Policy Forum of the Institute of Medicine in February 2014 to explore contemporary issues in human subjects protections as they pertain to cancer research, with the goal of identifying potential relevant policy actions. Clinical researchers, government officials, members of Institutional Review Boards, and patient advocates met to discuss clinical cancer research and oversight. This report examines current regulatory provisions that may not adequately protect patients or may be hindering research, and discusses potential strategies and actions to address those challenges"--Publisher's description.
588 ▼a Description based on online resource; title from resource home page (National Academies Press, viewed September 23, 2014).
650 0 ▼a Human experimentation in medicine ▼z United States ▼v Congresses.
650 0 ▼a Human experimentation in medicine ▼x Moral and ethical aspects ▼z United States ▼v Congresses.
650 0 ▼a Patients ▼x Civil rights ▼z United States ▼v Congresses.
650 0 ▼a Clinical trials ▼z United States ▼v Congresses.
650 0 ▼a Cancer ▼x Research ▼z United States ▼v Congresses.
650 0 ▼a Medical ethics ▼z United States ▼v Congresses.
65012 ▼a Human Experimentation ▼x standards ▼z United States ▼v Congresses.
65012 ▼a Clinical Trials as Topic ▼x standards ▼z United States ▼v Congresses.
65022 ▼a Patient Rights ▼z United States ▼v Congresses.
65022 ▼a Neoplasms ▼z United States ▼v Congresses.
65022 ▼a Ethics, Research ▼z United States ▼v Congresses.
65022 ▼a Ethics Committees, Research ▼z United States ▼v Congresses.
65022 ▼a Informed Consent ▼z United States ▼v Congresses.
65022 ▼a Research Subjects ▼z United States ▼v Congresses.
65022 ▼a Confidentiality ▼x standards ▼z United States ▼v Congresses.
65022 ▼a Electronic Health Records ▼x standards ▼z United States ▼v Congresses.
65022 ▼a Privacy ▼z United States ▼v Congresses.
65022 ▼a Researcher-Subject Relations ▼z United States ▼v Congresses.
650 7 ▼a BUSINESS & ECONOMICS / Business Ethics. ▼2 bisacsh
650 7 ▼a Cancer ▼x Research. ▼2 fast ▼0 (OCoLC)fst00845497
650 7 ▼a Clinical trials. ▼2 fast ▼0 (OCoLC)fst00864429
650 7 ▼a Human experimentation in medicine. ▼2 fast ▼0 (OCoLC)fst00963042
650 7 ▼a Human experimentation in medicine ▼x Moral and ethical aspects. ▼2 fast ▼0 (OCoLC)fst00963051
650 7 ▼a Medical ethics. ▼2 fast ▼0 (OCoLC)fst01014081
650 7 ▼a Patients ▼x Civil rights. ▼2 fast ▼0 (OCoLC)fst01055036
651 7 ▼a United States. ▼2 fast ▼0 (OCoLC)fst01204155
655 4 ▼a Electronic books.
655 7 ▼a Conference proceedings. ▼2 fast ▼0 (OCoLC)fst01423772
7001 ▼a Nass, Sharyl J., ▼e rapporteur.
7001 ▼a Patlak, Margie, ▼e rapporteur.
7102 ▼a National Cancer Policy Forum (U.S.), ▼e issuing body.
85640 ▼3 EBSCOhost ▼u http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=867638
938 ▼a EBSCOhost ▼b EBSC ▼n 867638
938 ▼a YBP Library Services ▼b YANK ▼n 12112208
990 ▼a 관리자